(2-Fluorophenylethynyl)trimethylsilane
(2-Fluorophenylethynyl)trimethylsilane (CAS 480439-33-6) is a fluorinated organic building block with the linear formula FC₆H₄CCSi(CH₃)₃ and a molecular weight of 192.30 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the construction of complex molecules. Its structure, featuring both a fluorinated phenyl ring and a protected alkynyl group, makes it suitable for various cross-coupling reactions and further functionalization in the development of novel materials and pharmaceuticals.
Organic Synthesis Intermediate
This compound is utilized as a key building block in the synthesis of diverse organic molecules. The presence of the fluorophenyl and trimethylsilyl-protected ethynyl moieties allows for selective chemical transformations.
Pharmaceutical Research
It can be employed in the development of new pharmaceutical agents where fluorinated aromatic systems are desired for modulating pharmacokinetic properties. The alkynyl group offers a versatile handle for subsequent synthetic steps.
Materials Science
The unique electronic and structural properties imparted by the fluorinated arylalkynyl motif make this compound a potential precursor for advanced materials, including organic electronics and polymers.
| Molecular weight | 192.30 |
|---|---|
| Linear formula | FC6H4CCSi(CH3)3 |
| Assay | 96% |
| Boiling point | 214-215 °C(lit.) |
| Density | 0.952 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.514(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Fluorophenylethynyl)trimethylsilane used for?
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(2-Fluorophenylethynyl)trimethylsilane is used as an intermediate in organic synthesis, particularly for constructing fluorinated organic molecules relevant to pharmaceutical research and materials science.
What is the CAS number and formula for (2-Fluorophenylethynyl)trimethylsilane?
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The CAS number is 480439-33-6 and the linear formula is FC₆H₄CCSi(CH₃)₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2-Fluorophenylethynyl)trimethylsilane with an assay of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (2-Fluorophenylethynyl)trimethylsilane be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator. This compound is a warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is this chemical packed, shipped, and exported by TSS?
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Yes, Tech Serve Solutions is a global supplier, exporter, and packager of fine chemicals.
How can I request a sample or quote for (2-Fluorophenylethynyl)trimethylsilane?
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Please contact our sales team through the website to request a sample or a quotation for (2-Fluorophenylethynyl)trimethylsilane.
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