(2-Hydroxyethyl)-β-cyclodextrin
(2-Hydroxyethyl)-β-cyclodextrin (CAS: 128446-32-2) is a chemically modified cyclodextrin, a cyclic oligosaccharide derived from starch. Its structure features a hydrophobic cavity and a hydrophilic exterior, enabling it to form inclusion complexes with various molecules. This property makes it valuable in analytical chemistry, particularly in chromatography and capillary electrophoresis, as well as in chemical synthesis and chelation applications.

Analytical and Chromatography
Utilised as a chiral mobile phase additive or stationary phase component in chromatography and capillary electrophoresis. Its ability to selectively complex with analytes aids in the separation of enantiomers and other chiral compounds.
Chelation and Complexation
Forms inclusion complexes with a variety of guest molecules, impacting their solubility, stability, and bioavailability. This is useful in analytical methods and for modifying the properties of other substances.
Chemical Synthesis
Serves as a reagent or auxiliary in organic synthesis. Its complexing ability can influence reaction pathways, stereoselectivity, or facilitate the solubilisation of substrates in different reaction media.
| Optical activity | [α]20/D 120 to 140°, c = 1 in H2O |
|---|---|
| Melting point | 260 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Extent Of Labeling | ~0.7 mol per mol cellulose |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Hydroxyethyl)-β-cyclodextrin used for?
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(2-Hydroxyethyl)-β-cyclodextrin is primarily used in analytical chemistry, particularly for chromatography and capillary electrophoresis as a chiral selector or mobile phase additive. It is also applied in chemical synthesis and for chelation/complexation applications due to its ability to form inclusion complexes.
What is the CAS number and formula for (2-Hydroxyethyl)-β-cyclodextrin?
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The CAS number for (2-Hydroxyethyl)-β-cyclodextrin is 128446-32-2. The provided data does not include the molecular formula.
What grade and purity does Tech Serve Solutions supply for (2-Hydroxyethyl)-β-cyclodextrin?
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Tech Serve Solutions supplies (2-Hydroxyethyl)-β-cyclodextrin with an extent of labelling of approximately 0.7 mol per mol cellulose, and optical activity of [α]20/D 120 to 140°, c = 1 in H2O. It is supplied as a technical/research grade material and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for (2-Hydroxyethyl)-β-cyclodextrin?
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When handling (2-Hydroxyethyl)-β-cyclodextrin, it is essential to wear Eyeshields and Gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The material has a Germany WGK rating of 3.
How is (2-Hydroxyethyl)-β-cyclodextrin packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packing and shipping procedures for all its chemical products, including (2-Hydroxyethyl)-β-cyclodextrin, to meet international standards.
How can I request a quote or sample for (2-Hydroxyethyl)-β-cyclodextrin?
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To request a quote or a sample of (2-Hydroxyethyl)-β-cyclodextrin, please contact our sales team through the TSS website or by phone, providing your specific requirements.
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