Tubulysin A
Tubulysin A (CAS: 205304-86-5, C43H65N5O10S) is a potent bioactive small molecule isolated from *Streptomyces sp.* This compound functions as a microtubule inhibitor, impacting cellular processes. It is typically supplied as a colorless or white film, with an assay of ≥95% (HPLC). Tubulysin A is commonly utilised in cell biology research, particularly in studies concerning cell signalling, neuroscience, and the cytoskeleton.
- IUPAC
- TubA

Cell Biology Research
Tubulysin A serves as a valuable tool in cell biology, enabling researchers to investigate cellular functions and pathways. Its ability to inhibit microtubules makes it useful for studying cell division and structural dynamics.
Cytoskeletal Studies
As a microtubule inhibitor, Tubulysin A is instrumental in understanding the role of the cytoskeleton. It aids in dissecting the complex mechanisms governing cell shape, motility, and intracellular transport.
Neuroscience Investigations
In the field of neuroscience, Tubulysin A can be employed to explore the involvement of microtubules in neuronal function and development. It assists in elucidating cellular processes critical to nervous system research.
| Molecular weight | 844.07 |
|---|---|
| Empirical formula | C43H65N5O10S |
| Assay | ≥95% (HPLC) |
| Form | film |
| Colour | colorless or white |
| Solubility | organic solvents: soluble |
| Storage temperature | 2-8°C |
| Biological source | from Streptomyces sp. |

Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tubulysin A used for?
+
Tubulysin A is used in research, primarily in cell biology, cell signalling, neuroscience, and studies involving the cytoskeleton and microtubule inhibition.
What are the CAS number and formula for Tubulysin A?
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The CAS number for Tubulysin A is 205304-86-5, and its empirical formula (Hill notation) is C43H65N5O10S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tubulysin A with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Tubulysin A be handled safely?
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Tubulysin A is classified as dangerous. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator. Avoid inhalation, ingestion, and contact with skin and eyes. Ensure adequate ventilation.
How is Tubulysin A shipped?
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Tubulysin A is shipped on wet ice and should be stored at 2-8°C.
How can I request a quote or sample for Tubulysin A?
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Please contact our sales team to request a quote or sample for Tubulysin A.
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