3-Thiopheneacetonitrile
3-Thiopheneacetonitrile (CAS: 13781-53-8, Formula: C6H5NS) is a chemical compound with a molecular weight of 123.18 g/mol. It serves as a valuable building block in organic synthesis, particularly within the realm of heterocyclic chemistry. Its primary applications involve its use as an intermediate in the creation of more complex organic molecules, contributing to advancements in chemical research and development.
- IUPAC
- 3-Thienylacetonitrile
- Synonyms
- 3-Thienylacetonitrile
Synthesis of Acrylonitrile Derivatives
3-Thiopheneacetonitrile is utilised in the synthesis of substituted acrylonitrile compounds. For example, it has been employed in the preparation of (E)-3-phenyl-2-(3-thienyl) acrylonitrile and (Z)-3-(4-methylphenyl)-2-(3-thienyl) acrylonitrile.
Heterocyclic Compound Intermediary
As a thiophene derivative, this compound acts as a key intermediate for constructing more elaborate heterocyclic structures. Its nitrile group and thiophene ring offer versatile reaction sites for further chemical transformations.
Organic Synthesis Building Block
This chemical is broadly applicable as a building block in general organic synthesis. Its structure allows for incorporation into diverse molecular frameworks, supporting research and development in various chemical fields.
| Molecular weight | 123.18 |
|---|---|
| Empirical formula | C6H5NS |
| Assay | 96% |
| Boiling point | 124-125 °C/16 mmHg(lit.) |
| Density | 1.08 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.545(lit.) |
| Application | 3-Thiopheneacetonitrile was used in the synthesis of:• (E)-3-phenyl-2-(3-thienyl) acrylonitrile1• (Z)-3-(4-methylphenyl)-2-(3-thienyl) acrylonitrile2 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 119 °C / 246.2 °F |
| Transport (UN / ADR) | UN 3276 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Thiopheneacetonitrile used for?
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3-Thiopheneacetonitrile is primarily used as a building block and intermediate in organic synthesis, particularly for creating acrylonitrile derivatives and other heterocyclic compounds.
What is the CAS number and chemical formula for 3-Thiopheneacetonitrile?
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The CAS number is 13781-53-8, and the chemical formula is C6H5NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Thiopheneacetonitrile with an assay of 96%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Thiopheneacetonitrile be handled safely?
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Handling requires caution due to hazards including harmful ingestion, skin contact, inhalation, and irritation to skin, eyes, and respiratory tract. Use appropriate personal protective equipment such as eyeshields, gloves, and a suitable respirator. Ensure good ventilation.
Is 3-Thiopheneacetonitrile available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Thiopheneacetonitrile, and can facilitate international shipments.
How can I request a sample or quote for 3-Thiopheneacetonitrile?
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To request a sample or obtain a quote, please contact our sales department through the website or by phone, providing your requirements and shipping details.
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