3-Thienylzinc iodide solution
3-Thienylzinc iodide solution (CAS: 172035-85-7) is an organozinc reagent with a molecular weight of 275.43 g/mol. Supplied as a 0.5 M solution in Tetrahydrofuran (THF), this compound is a valuable tool in organic synthesis, particularly for cross-coupling reactions. Its reactivity allows for the introduction of the 3-thienyl group into various organic molecules, facilitating the construction of complex chemical structures relevant to materials science and medicinal chemistry.
Cross-Coupling Reactions
3-Thienylzinc iodide is a key nucleophilic partner in palladium-catalysed cross-coupling reactions, such as Negishi coupling. It efficiently transfers the 3-thienyl moiety to electrophilic substrates, enabling the synthesis of biaryl and heteroaryl compounds.
Synthesis of Thiophene Derivatives
This reagent serves as a direct precursor for creating a wide range of functionalised thiophenes. These derivatives are important building blocks in the development of organic electronic materials, pharmaceuticals, and agrochemicals.
Organometallic Chemistry
As an organozinc halide, it falls under the category of organometallic reagents. Its controlled reactivity makes it suitable for various transformations in modern synthetic organic chemistry, offering an alternative to other organometallic species.
| Molecular weight | 275.43 |
|---|---|
| Empirical formula | C4H3ISZn |
| Boiling point | 65 °C |
| Density | 1.011 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Thienylzinc iodide solution used for?
+
3-Thienylzinc iodide solution (CAS: 172035-85-7) is primarily used in organic synthesis, particularly in palladium-catalysed cross-coupling reactions like Negishi coupling, for the introduction of the 3-thienyl group into organic molecules. It is also a key reagent for synthesising various functionalised thiophene derivatives.
What is the CAS number and formula for 3-Thienylzinc iodide solution?
+
The CAS number for 3-Thienylzinc iodide solution is 172035-85-7. The empirical formula (Hill notation) is C4H3ISZn.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Thienylzinc iodide solution at a concentration of 0.5 M in THF. This is a technical/research grade material and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Thienylzinc iodide solution be handled safely?
+
3-Thienylzinc iodide solution is a highly flammable liquid and vapour (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment (P210, P261, P281, P305 + P351 + P338).
How is 3-Thienylzinc iodide solution packed and shipped?
+
This product is classified under UN 2924, 8(3) / PGII, indicating it is a corrosive liquid, flammable, and toxic. It is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for hazardous materials.
How can I request a quote or sample?
+
To request a quote or a sample of 3-Thienylzinc iodide solution, please contact the Tech Serve Solutions sales team through our website or by phone. Please specify the quantity required and your delivery location.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis