3-Thienylboronic acid
3-Thienylboronic acid (CAS: 6165-69-1), with the molecular formula C4H5BO2S and a molecular weight of 127.96, is a versatile organoboron compound. It is a key building block in organic synthesis, particularly for forming carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. Its applications span across pharmaceutical research and material science, where it is used to construct complex molecular architectures incorporating a thiophene moiety. Supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- (Thiophene-3-yl)boronic acid,3-Thiopheneboric acid,3-Thiopheneboronic acid,3-Thiophenylboronic acid,Thiophene-3-boronic acid
- Synonyms
- (Thiophene-3-yl)boronic acid3-Thiopheneboric acid3-Thiopheneboronic acid3-Thiophenylboronic acidThiophene-3-boronic acid
Suzuki-Miyaura Cross-Coupling
3-Thienylboronic acid is frequently employed as a coupling partner in palladium-catalysed Suzuki-Miyaura reactions. This enables the efficient synthesis of biaryl compounds and other complex organic molecules containing the thiophene ring system.
Pharmaceutical Intermediate
This boronic acid derivative serves as a valuable intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its incorporation can introduce specific electronic and steric properties to target molecules.
Materials Science
It is utilized in the development of advanced materials, such as organic semiconductors and conjugated polymers. The thiophene unit's electronic characteristics are beneficial for applications in organic electronics.
Agrochemical Synthesis
The compound can be used in the synthesis of novel agrochemicals, contributing to the development of new crop protection agents.
| Molecular weight | 127.96 |
|---|---|
| Empirical formula | C4H5BO2S |
| Assay | ≥95.0% |
| Melting point | 164-169 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Thienylboronic acid primarily used for?
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3-Thienylboronic acid is primarily used as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the development of pharmaceuticals and advanced materials.
What is the CAS number and molecular formula for 3-Thienylboronic acid?
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The CAS number for 3-Thienylboronic acid is 6165-69-1, and its molecular formula is C4H5BO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Thienylboronic acid with an assay of ≥95.0%. This product is intended for research and development use and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Thienylboronic acid be handled safely?
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3-Thienylboronic acid is classified as a Warning substance. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is also harmful if swallowed (H302). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Ensure good ventilation. Avoid breathing dust and contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for full details.
Is 3-Thienylboronic acid available for international export?
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Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including 3-Thienylboronic acid. We adhere to all necessary regulations for international shipping.
How can I request a sample or quote for 3-Thienylboronic acid?
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To request a sample or a quotation, please contact our sales department via the website or direct email, providing your contact details and the required quantity.
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