(3,5-Difluorophenylethynyl)trimethylsilane

CAS 445491-09-8(CH3)3SiC≡CC6H3F2Chemical Synthesis

(3,5-Difluorophenylethynyl)trimethylsilane (CAS 445491-09-8) is a fluorinated alkynyl compound with the linear formula (CH3)3SiC≡CC6H3F2 and a molecular weight of 210.30 g/mol. This organosilicon compound serves as a valuable building block in organic synthesis. Its structure, featuring a difluorophenyl group and a trimethylsilyl-protected alkyne, makes it useful for introducing specific functionalities into more complex molecules, particularly in materials science and pharmaceutical research.

Synonyms: (CH3)3SiC≡CC6H3F2

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(3,5-Difluorophenylethynyl)trimethylsilane ((CH3)3SiC≡CC6H3F2) — chemical structure, CAS 445491-09-8; Chemistry, fine chemical supplied by Tech Serve Solutions

AlkynylBuilding BlocksC8-C12Chemical SynthesisFluorinated Building BlocksHalogenated HydrocarbonsOrganic Building Blocks

01 /Applications

Organic Synthesis Intermediate

Serves as a key building block for the synthesis of complex organic molecules. The trimethylsilyl group protects the alkyne functionality, allowing for selective reactions at other sites before deprotection.

Materials Science

Used in the development of novel materials, potentially including polymers and organic electronic components, where the fluorinated aromatic ring can influence electronic and physical properties.

Pharmaceutical Research

Incorporated into the design of potential drug candidates, leveraging the unique electronic and metabolic stability characteristics often conferred by fluorine atoms.

Fluorinated Compound Synthesis

A valuable reagent for introducing the 3,5-difluorophenylacetylene moiety into various molecular scaffolds.

02 /Properties

Molecular weight	210.30
Linear formula	(CH3)3SiC≡CC6H3F2
Assay	98%
Boiling point	200-201 °C(lit.)
Density	0.995 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.4920(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	74 °C / 165.2 °F
Transport (UN / ADR)	NA 1993 / PGIII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

445491-09-8

MDL number

MFCD04039981

PubChem substance

24881238

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (3,5-Difluorophenylethynyl)trimethylsilane used for?

This compound is primarily used as a building block in organic synthesis, particularly in materials science and pharmaceutical research for creating complex fluorinated molecules.

What are the CAS number and formula for this product?

The CAS number is 445491-09-8, and the linear formula is (CH3)3SiC≡CC6H3F2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at an assay of 98%. It is suitable for research and development purposes. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.

How should (3,5-Difluorophenylethynyl)trimethylsilane be handled?

Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, as it is a combustible liquid with a flash point of 74 °C (165.2 °F). Refer to the safety data sheet for detailed handling instructions.

Is this chemical suitable for export and shipping?

Yes, this chemical is classified under UN 1993, Packing Group III, and is suitable for export and shipping by Tech Serve Solutions, a global supplier and exporter.