(3,4-Dimethoxyphenyl)acetyl chloride
(3,4-Dimethoxyphenyl)acetyl chloride, CAS 10313-60-7, has the linear formula (CH3O)2C6H3CH2COCl and a molecular weight of 214.65 g/mol. This compound, also known as Homoveratryl chloride, functions as a key building block in organic synthesis. It is primarily utilised in the preparation of various complex organic molecules, including nitriles and naphthalene derivatives, offering a valuable reactive intermediate for chemical research and development.
- IUPAC
- Homoveratryl chloride
- Synonyms
- (CH3O)2C6H3CH2COClHomoveratryl chloride
Synthesis of Homoveratryl Nitrile (HVN)
(3,4-Dimethoxyphenyl)acetyl chloride serves as a precursor in the synthesis of homoveratryl nitrile (HVN). This conversion is a fundamental step in constructing specific nitrogen-containing organic compounds.
Preparation of Naphthalene Sulfonyl Compounds
This acid halide is employed in the preparation of isomeric naphthalene sulfonyl compounds. Specifically, it facilitates the synthesis of 1- and 2-[{2-(3,4-dimethoxyphenyl)ethyl}methylamino] naphthalene derivatives.
Organic Synthesis Building Block
As a reactive acid halide and organic building block, (3,4-Dimethoxyphenyl)acetyl chloride is valuable for introducing the 3,4-dimethoxyphenylacetyl moiety into various molecular structures during complex organic synthesis.
| Molecular weight | 214.65 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2COCl |
| Assay | 98% |
| Boiling point | 118-119 °C/0.2 mmHg(lit.) |
| Density | 1.245 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5489(lit.) |
| Application | (3,4-Dimethoxyphenyl)acetyl chloride (Homoveratryl chloride) has been used in the preparation of:• homo veratryl nitrile (HVN)1• isomeric naphthalene sulphonyl compounds, 1- and 2-[{2-(3,4-dimethoxyphenyl)ethyl}methylamino] sulphonyl naphthalenes1 |
| Melting point | 40-43 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3,4-Dimethoxyphenyl)acetyl chloride used for?
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(3,4-Dimethoxyphenyl)acetyl chloride is primarily used as a building block in organic synthesis, notably in the preparation of homoveratryl nitrile (HVN) and specific isomeric naphthalene sulfonyl compounds.
What is the CAS number and formula for (3,4-Dimethoxyphenyl)acetyl chloride?
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The CAS number for (3,4-Dimethoxyphenyl)acetyl chloride is 10313-60-7, and its linear formula is (CH3O)2C6H3CH2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (3,4-Dimethoxyphenyl)acetyl chloride with a minimum assay of 98%. This product is supplied for research and manufacturing purposes; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should (3,4-Dimethoxyphenyl)acetyl chloride be handled?
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(3,4-Dimethoxyphenyl)acetyl chloride is a corrosive material that can cause severe skin burns and eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection suitable for acid chlorides. Ensure adequate ventilation.
How is (3,4-Dimethoxyphenyl)acetyl chloride shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. (3,4-Dimethoxyphenyl)acetyl chloride is securely packaged and shipped in compliance with all relevant international regulations for hazardous materials, including UN 3261, Class 8, Packing Group II.
How can I request a sample or quote for (3,4-Dimethoxyphenyl)acetyl chloride?
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To request a sample or quote for (3,4-Dimethoxyphenyl)acetyl chloride, please use the contact form on our website or contact our sales department directly. Please provide your details and the quantity required.
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