2′,3′-Dideoxycytidine 5′-triphosphate sodium salt
2′,3′-Dideoxycytidine 5′-triphosphate sodium salt (CAS: 132619-66-0) is a biochemical reagent with a molecular weight of 451.16 g/mol. Primarily recognised as a substrate analog, this compound has been utilised in crystallographic studies of DNA polymerase β complexes. These studies provide insights into potential inhibitory mechanisms against enzymes such as HIV reverse transcriptase, highlighting its significance in biochemical research and drug discovery.
- IUPAC
- ddCTP
- Synonyms
- ddCTP sodium salt
Enzyme Inhibition Studies
Used to investigate inhibitory activity against viral enzymes like HIV reverse transcriptase, particularly through crystallographic studies of enzyme-DNA complexes.
Biochemical Research
Serves as a valuable substrate analog in biochemical assays and research, aiding in the understanding of DNA synthesis and polymerase mechanisms.
Structural Biology
Applied in X-ray crystallography to determine the structural basis of enzyme-substrate interactions and potential drug binding sites.
| Molecular weight | 451.16 |
|---|---|
| Empirical formula | C9H16N3O12P3 |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Application | Complexes of ddCTP with DNA polymerase β were studied by x-ray crystallography, with implications for inhibitory activity against HIV reverse transcriptase.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt used for?
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2′,3′-Dideoxycytidine 5′-triphosphate sodium salt is primarily used as a substrate analog in biochemical research, including studies of DNA polymerase β and its implications for inhibiting enzymes like HIV reverse transcriptase.
What are the CAS number and empirical formula for 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt?
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The CAS number is 132619-66-0 and the empirical formula (Hill notation) is C9H16N3O12P3.
What grade and purity does Tech Serve Solutions supply for 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt?
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Tech Serve Solutions supplies 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt with an assay of ≥90% (HPLC). We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt be handled safely?
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When handling, ensure the use of Eyeshields and Gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 3 in Germany.
How is 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt packed and shipped?
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This product is typically stored at −20°C. Tech Serve Solutions can export this chemical globally, adhering to all relevant shipping and handling regulations.
How can I request a quote or sample for 2′,3′-Dideoxycytidine 5′-triphosphate sodium salt?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing the product name and CAS number.
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