2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt

CAS 68726-28-3C10H16N5O12P3Biochemicals & Reagents

2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt (CAS 68726-28-3) is a critical biochemical reagent. With a molecular weight of 491.18 g/mol, this nucleotide analogue functions as a chain terminator inhibitor in nucleic acid synthesis. It is also recognised for its role as an inhibitor of telomerase enzymes, making it valuable in molecular biology research and diagnostics. TSS supplies this compound for laboratory use.

IUPAC: ddGTP
Synonyms: 2′,3′-Dideoxyguanosine-5′-triphosphateddGTPDideoxyguanosine triphosphate

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2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt (C10H16N5O12P3) — chemical structure, CAS 68726-28-3; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyD-DIFNucleosidesNucleotidesOligonucleotidesNucleotide Analogs More...

01 /Applications

Chain Terminator Inhibitor

2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) acts as a chain terminator, disrupting nucleic acid extension processes. This property is fundamental in molecular biology techniques like DNA sequencing.

Telomerase Inhibition

ddGTP is utilised as an inhibitor of telomerase, an enzyme critical for maintaining telomere length. Research into telomerase function and its role in diseases often employs this compound.

Biochemical Research

As a modified nucleotide, ddGTP is an essential tool in various biochemical and cell biology studies. Its applications extend to the investigation of nucleotide metabolism and enzyme kinetics.

02 /Properties

Molecular weight	491.18
Empirical formula	C10H16N5O12P3
Assay	≥90% (HPLC)
Storage temperature	−20°C
Application	2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) is use as a chain terminator inhibitor and a inhibitor of telomerase(s).

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

68726-28-3

MDL number

MFCD00079152

05 /Additional specifications

Gene Information	human ... HRAS(3265)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt used for?

2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt (CAS 68726-28-3) is used as a chain terminator inhibitor and a telomerase inhibitor in biochemical and cell biology research.

What are the CAS number and molecular formula for this compound?

The CAS number is 68726-28-3. The empirical formula (Hill notation) is C10H16N5O12P3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt with an assay of ≥90% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt be handled?

When handling, use appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Dispose of according to local regulations. The WGK is 3.

How is this chemical shipped and exported?

This chemical is stored at -20°C and can be shipped and exported globally by Tech Serve Solutions. Please contact us for specific shipping requirements.

How can I request a sample or quote?

To request a sample or a quote for 2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt, please use the contact form on our website or call our sales team directly.