2′,3′-O-Isopropylideneguanosine
2′,3′-O-Isopropylideneguanosine (CAS: 362-76-5) is a guanosine derivative with the molecular formula C13H17N5O5 and a molecular weight of 323.30. This compound is primarily used as a building block in the synthesis of modified nucleosides and nucleotides. Its unique isopropylidene protection allows for selective reactions at other positions, making it a valuable reagent in biochemical research and the development of therapeutic agents. TSS supplies this chemical for laboratory and research applications.
- Synonyms
- 2′,3′-O-Isopropylideneguanosine
Nucleoside Analog Synthesis
2′,3′-O-Isopropylideneguanosine serves as a key intermediate in the synthesis of various nucleoside analogs. The isopropylidene group protects the 2' and 3' hydroxyls, enabling targeted modifications at other sites of the guanosine molecule.
Cap Analog Precursor
Derivatives of 2′,3′-O-Isopropylideneguanosine are employed as cap analogs in mRNA research. These analogs can be incorporated into synthetic mRNA to study translation initiation and stability.
Biochemical Research Reagent
As a protected nucleoside, this compound is a valuable reagent for researchers investigating nucleic acid chemistry, enzyme mechanisms, and the development of novel oligonucleotide-based therapeutics.
| Molecular weight | 323.30 |
|---|---|
| Empirical formula | C13H17N5O5 |
| Application | 2′,3′-O-Isopropylideneguanosine derivatives may be used as cap analogs. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,3′-O-Isopropylideneguanosine used for?
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2′,3′-O-Isopropylideneguanosine is used as an intermediate in the synthesis of nucleoside analogs and as a precursor for cap analogs in mRNA research, making it valuable in biochemical studies.
What are the CAS number and formula for 2′,3′-O-Isopropylideneguanosine?
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The CAS number is 362-76-5, and its empirical formula (Hill notation) is C13H17N5O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,3′-O-Isopropylideneguanosine for research and laboratory use. Purity and grade information are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should 2′,3′-O-Isopropylideneguanosine be handled safely?
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When handling 2′,3′-O-Isopropylideneguanosine, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. This compound is classified under WGK Germany 3, indicating a high hazard to water.
Is 2′,3′-O-Isopropylideneguanosine a controlled substance?
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The provided data does not indicate that 2′,3′-O-Isopropylideneguanosine is a controlled substance.
How is 2′,3′-O-Isopropylideneguanosine packed, shipped, and exported?
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Tech Serve Solutions securely packs chemicals in compliance with international shipping regulations. We offer global export services for research and industrial clients.
How can I request a sample or quote for 2′,3′-O-Isopropylideneguanosine?
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To request a sample or a quotation, please use the contact form on our website or email our sales department, referencing the product name and CAS number (362-76-5).
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