(1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol
(1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol (CAS 167752-95-6) is a chiral cyclohexanol derivative with a molecular weight of 260.41 g/mol. This compound serves as a valuable chiral building block and auxiliary in asymmetric synthesis. Its defined stereochemistry allows for controlled induction of chirality in various organic transformations, making it instrumental in the synthesis of enantiomerically pure compounds for research and development purposes.
- Synonyms
- 167752-95-6(CH3)2CHC6H9[C(CH3)2C6H5]OH
![(1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol ((CH3)2CHC6H9[C(CH3)2C6H5]OH) — chemical structure, CAS 167752-95-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F167752-95-6.png&w=3840&q=75)
Chiral Auxiliary in Asymmetric Synthesis
This cyclohexanol derivative acts as a chiral auxiliary, enabling the stereoselective synthesis of complex organic molecules. It can be employed to direct the stereochemical outcome of reactions such as alkylations, Diels-Alder reactions, and conjugate additions.
Organic Building Block
As an organic building block, it provides a defined stereochemical framework for constructing more elaborate chiral structures. Its unique bulky substituents can influence reactivity and selectivity in synthetic pathways.
Research and Development
Utilised in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chiral compounds with potential applications in pharmaceuticals or materials science.
| Molecular weight | 260.41 |
|---|---|
| Linear formula | (CH3)2CHC6H9[C(CH3)2C6H5]OH |
| Assay | 98% |
| Optical activity | [α]20/D −35°, c = 1 in ethanol |
| Optical purity | ee: 99% (HPLC) |
| Application | Cyclohexyl-based chiral auxiliary that provides equal or greater levels of asymmetric induction when compared to menthol or 8-phenylmenthol in a variety of reactions.1,2,3,4 |
| Melting point | 68-71 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol used for?
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(1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol is primarily used as a chiral auxiliary and building block in asymmetric synthesis for the stereoselective preparation of enantiomerically enriched compounds.
What are the CAS number and formula for this chemical?
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The CAS number is 167752-95-6. The linear formula is (CH3)2CHC6H9[C(CH3)2C6H5]OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98% and an optical purity of ee: 99% (HPLC). This is a research or technical grade material and is not represented as USP, BP, or EP.
What are the safety and handling considerations?
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This compound is classified under WGK 2 (Germany). Appropriate personal protective equipment, including gloves and eye protection, should be used when handling. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive information.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol.
How can I request a sample or quote?
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To request a sample or a quote for (1R,2S,4R)-(−)-4-(1-Methylethyl)-2-(1-methyl-1-phenylethyl)cyclohexanol, please contact our sales team through the website or by phone.
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