(1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol
(1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol (CAS: 1228077-92-6) is a valuable chiral building block with the molecular formula C22H25NO3 and a molecular weight of 351.44 g/mol. This enantiomerically enriched compound is utilised in asymmetric synthesis and organic chemical synthesis. Its defined stereochemistry makes it suitable for constructing complex chiral molecules, serving as a key intermediate in advanced chemical research and development.
- Synonyms
- C22H25NO3

Chiral Building Block
This compound serves as a crucial stereodefined building block in the synthesis of complex chiral molecules. Its defined (1R,2S)-trans configuration is essential for creating enantiomerically pure target structures in pharmaceutical and fine chemical research.
Asymmetric Synthesis
Utilised in asymmetric synthesis methodologies to introduce specific chirality. It can be employed in reactions where stereochemical control is paramount, contributing to the development of enantioselective processes.
Organic Synthesis Intermediate
Functions as an intermediate in multi-step organic synthesis pathways. The Fmoc-protected amine and the cyclohexanol moiety offer versatile reaction handles for further chemical transformations.
| Molecular weight | 351.44 |
|---|---|
| Empirical formula | C22H25NO3 |
| Assay | ≥96.5% (GC)97% |
| Optical purity | enantiomeric excess: ≥97.5% |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol used for?
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(1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol is primarily used as a chiral building block in asymmetric synthesis and organic chemical synthesis.
What is the CAS number and formula for (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol?
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The CAS number is 1228077-92-6 and the empirical formula is C22H25NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol with an assay of ≥96.5% (GC) or 97%, and an enantiomeric excess of ≥97.5%. This product is not classified as USP, BP, or EP grade.
How should (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust, fumes, or spray. Ensure adequate ventilation. It is classified as causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How is (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol shipped?
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This chemical is stored at 2-8°C and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol?
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Please contact our sales department through the website or by phone to request a sample or a quotation for (1R,2S)-trans-2-(Fmoc-aminomethyl)cyclohexanol.
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