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2-(Trifluoromethyl)benzylamine

CAS 3048-01-9CF3C6H4CH2NH2Chemical Synthesis

2-(Trifluoromethyl)benzylamine (CAS: 3048-01-9) is a valuable organic compound with the linear formula CF3C6H4CH2NH2 and a molecular weight of 175.15 g/mol. This primary amine, featuring a trifluoromethyl group on the phenyl ring, serves as a key building block in complex chemical synthesis. Its unique structure makes it suitable for incorporation into diverse molecular architectures, particularly in the development of novel chemical entities.

IUPAC
2-(Aminomethyl)benzotrifluoride
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2-(Trifluoromethyl)benzylamine (CF3C6H4CH2NH2) — chemical structure, CAS 3048-01-9; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisNitrogen Compounds
01 /Applications

Chemical Synthesis

2-(Trifluoromethyl)benzylamine is utilised as a versatile building block in organic synthesis. Its amine functionality allows for derivatisation, while the trifluoromethylphenyl moiety can impart specific electronic and lipophilic properties to target molecules.

Pharmaceutical Intermediates

This compound can serve as an intermediate in the synthesis of pharmaceutically active compounds. The trifluoromethyl group is often incorporated to enhance metabolic stability or binding affinity of drug candidates.

Research and Development

As a readily available building block, it is employed in academic and industrial research laboratories for the creation of new chemical structures and the exploration of novel reaction pathways.

02 /Properties
Molecular weight175.15
Linear formulaCF3C6H4CH2NH2
Assay98%
Density1.249 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.471(lit.)
Application2-(Trifluoromethyl)benzylamine may be used in chemical synthesis.
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point69 °C / 156.2 °F
Transport (UN / ADR)UN 2735 8/PG 3
Water hazard class (WGK, DE)2
Hazard codes (EU)C
Risk statements (R)22-34-52/53
Safety statements (S)26-36/37/39-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
3048-01-9
MDL number
MFCD00010297
PubChem substance
24855976
Beilstein registry
1103424
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-(Trifluoromethyl)benzylamine used for?

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2-(Trifluoromethyl)benzylamine is primarily used in chemical synthesis as a building block, potentially serving as an intermediate in the development of pharmaceuticals and other fine chemicals.

What are the CAS number and formula for 2-(Trifluoromethyl)benzylamine?

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The CAS number is 3048-01-9, and the linear formula is CF3C6H4CH2NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-(Trifluoromethyl)benzylamine with a purity of 98%. We do not represent this product as USP, BP, or EP grade.

How should 2-(Trifluoromethyl)benzylamine be handled safely?

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2-(Trifluoromethyl)benzylamine is classified as corrosive and harmful if swallowed. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Avoid contact with skin, eyes, and clothing. Refer to the safety data sheet for comprehensive handling information.

Is 2-(Trifluoromethyl)benzylamine a controlled substance?

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The provided data does not indicate that 2-(Trifluoromethyl)benzylamine is a controlled substance.

How is 2-(Trifluoromethyl)benzylamine packed and exported?

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Tech Serve Solutions packs and exports chemicals in compliance with international shipping regulations. Specific packaging details are available upon request.

How can I request a sample or quote for 2-(Trifluoromethyl)benzylamine?

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To request a sample or obtain a quote for 2-(Trifluoromethyl)benzylamine, please contact our sales team through the TSS website or by phone.

Need 2-(Trifluoromethyl)benzylamine in a specific grade or volume?