2-(Trifluoromethyl)benzyl bromide
2-(Trifluoromethyl)benzyl bromide (CAS 395-44-8, CF3C6H4CH2Br) is a halogenated hydrocarbon with a molecular weight of 239.03 g/mol. Supplied at 96% purity, this organic building block is primarily utilised in chemical synthesis. Its reactive benzylic bromide functionality and the electron-withdrawing trifluoromethyl group make it a valuable intermediate for introducing the 2-(trifluoromethyl)benzyl moiety into various molecular structures. Tech Serve Solutions offers this compound for research and development purposes.
- IUPAC
- α′-Bromo-α,α,α-trifluoro-o-xylene
- Synonyms
- α′-Bromo-α,α,α-trifluoro-o-xylene

Organic Synthesis Intermediate
This compound serves as a versatile intermediate in organic synthesis. It can be used for the alkylation of nucleophiles, facilitating the introduction of the 2-(trifluoromethyl)benzyl group into target molecules.
Pharmaceutical and Agrochemical Research
The presence of the trifluoromethyl group often imparts desirable pharmacokinetic properties, making this compound a potential building block in the discovery and development of new pharmaceutical agents and agrochemicals.
Material Science Applications
As a functionalised aromatic compound, 2-(trifluoromethyl)benzyl bromide may find utility in the synthesis of specialised polymers or advanced materials where its unique structural features are beneficial.
| Molecular weight | 239.03 |
|---|---|
| Linear formula | CF3C6H4CH2Br |
| Assay | 96% |
| Boiling point | 72 °C/7.5 mmHg(lit.) |
| Density | 1.571 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.494(lit.) |
| Application | 2-(Trifluoromethyl)benzyl bromide may be used in chemical synthesis. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 83 °C / 181.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)benzyl bromide used for?
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2-(Trifluoromethyl)benzyl bromide is used as an intermediate in chemical synthesis, particularly for introducing the 2-(trifluoromethyl)benzyl group into organic molecules, and has potential applications in pharmaceutical, agrochemical, and material science research.
What is the CAS number and chemical formula for 2-(Trifluoromethyl)benzyl bromide?
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The CAS number is 395-44-8 and the chemical formula is CF3C6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)benzyl bromide at a purity of 96%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 2-(Trifluoromethyl)benzyl bromide be handled?
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2-(Trifluoromethyl)benzyl bromide is classified as Danger, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation and follow emergency procedures if exposure occurs.
How is 2-(Trifluoromethyl)benzyl bromide packed, shipped, and exported?
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2-(Trifluoromethyl)benzyl bromide is packed in compliance with international shipping regulations for hazardous materials, including UN 3265, Class 8, Packing Group II. TSS exports globally.
How can I request a sample or quote for 2-(Trifluoromethyl)benzyl bromide?
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To request a sample or a quotation, please contact our sales team through the TSS website or by phone, providing your specific requirements and shipping details.
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