2-Iodosobenzoic acid

CAS 304-91-6OIC6H4CO2HMolecular Biology

2-Iodosobenzoic acid (CAS 304-91-6) is an organic compound with the formula OIC6H4CO2H and a molar mass of 264.02 g/mol. It is a key reagent primarily utilised for the chemical cleavage of tryptophanyl peptide bonds. This compound finds applications in biochemical research, particularly within the fields of proteomics and mass spectrometry, aiding in protein analysis.

IUPAC: IBA

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2-Iodosobenzoic acid (OIC6H4CO2H) — chemical structure, CAS 304-91-6; Life Science, fine chemical supplied by Tech Serve Solutions

Mass SpectrometryMolecular BiologyProteomics

01 /Applications

Chemical Cleavage of Tryptophanyl Peptide Bonds

2-Iodosobenzoic acid is specifically employed for the selective cleavage of peptide bonds at the C-terminal side of tryptophan residues. This process is essential in protein sequencing and structural analysis.

Proteomics and Mass Spectrometry

In proteomics, this reagent aids in the preparation of protein samples for analysis by mass spectrometry. It facilitates the generation of specific peptide fragments required for identification and characterisation.

Molecular Biology Research

This compound serves as a valuable tool in molecular biology for researchers investigating protein structures and functions. Its specific cleavage activity allows for targeted manipulation of peptide chains.

02 /Properties

Molecular weight	264.02
Linear formula	OIC6H4CO2H
Storage temperature	−20°C
Application	For cleavage of tryptophanyl peptide bonds.
Melting point	230 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

304-91-6

MDL number

MFCD00002401

PubChem substance

24896131

Beilstein registry

1939973

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Iodosobenzoic acid used for?

2-Iodosobenzoic acid is primarily used for the chemical cleavage of tryptophanyl peptide bonds in protein analysis, with applications in proteomics and mass spectrometry.

What is the CAS number and chemical formula for 2-Iodosobenzoic acid?

The CAS number for 2-Iodosobenzoic acid is 304-91-6, and its chemical formula is OIC6H4CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-Iodosobenzoic acid as a reagent for research and laboratory use. Purity information is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.

How should 2-Iodosobenzoic acid be handled?

2-Iodosobenzoic acid is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US). Ensure adequate ventilation.

How is 2-Iodosobenzoic acid shipped and exported?

Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Iodosobenzoic acid, adhering to all necessary shipping and export regulations.