2-Nitro-5-thiocyanatobenzoic acid
2-Nitro-5-thiocyanatobenzoic acid (CAS: 30211-77-9), with the molecular formula O2NC6H3(SCN)CO2H and a molecular weight of 224.19 g/mol, is a specialized reagent. It is primarily utilized in biochemical research for the chemical cleavage of proteins, facilitating downstream analyses in fields such as mass spectrometry and proteomics. This compound serves as a valuable tool for protein sequencing and structural studies.
- IUPAC
- 2-Nitro-5-thiocyanobenzoic acid,NTCB
Chemical Protein Cleavage
2-Nitro-5-thiocyanatobenzoic acid is employed for the specific chemical cleavage of peptide bonds in proteins. This process is crucial for fragmenting large proteins into smaller peptides for subsequent analysis.
Mass Spectrometry and Proteomics
The peptides generated by the cleavage of proteins with this reagent are ideal for analysis by mass spectrometry. This aids in protein identification, characterisation, and the study of proteomes.
Protein Sequencing
By selectively cleaving proteins at specific sites, 2-Nitro-5-thiocyanatobenzoic acid assists in determining the amino acid sequence of proteins, contributing to fundamental biological research.
| Molecular weight | 224.19 |
|---|---|
| Linear formula | O2NC6H3(SCN)CO2H |
| Storage temperature | 2-8°C |
| Melting point | 156-157 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitro-5-thiocyanatobenzoic acid used for?
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2-Nitro-5-thiocyanatobenzoic acid is primarily used for the chemical cleavage of proteins, which is essential for protein sequencing, mass spectrometry, and proteomics research.
What is the CAS number and molecular formula?
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The CAS number for 2-Nitro-5-thiocyanatobenzoic acid is 30211-77-9, and its molecular formula is O2NC6H3(SCN)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitro-5-thiocyanatobenzoic acid, but the specific grade and purity are not detailed in the provided data. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 2-Nitro-5-thiocyanatobenzoic acid be handled and stored?
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2-Nitro-5-thiocyanatobenzoic acid is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Recommended storage is at 2-8°C.
Is this product suitable for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Nitro-5-thiocyanatobenzoic acid. We can arrange for its export.
How can I request a quote or sample?
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To request a quote or a sample of 2-Nitro-5-thiocyanatobenzoic acid, please contact our sales team through the dedicated channels on the Tech Serve Solutions website.
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