2-Iminobiotin N-hydroxysuccinimide ester hydrobromide
2-Iminobiotin N-hydroxysuccinimide ester hydrobromide (CAS 76939-67-8), with the molecular formula C14H20N4O4S · HBr and a molecular weight of 421.31 g/mol, is a chemical reagent primarily employed in biotinylation applications. This compound is instrumental in the modification of proteins and is utilised within molecular biology, proteomics, and protein structural analysis. Its reactive nature allows for specific conjugation to amine groups, facilitating downstream detection and purification.
- IUPAC
- N-Hydroxysuccinimido-2-iminobiotin
- Synonyms
- N-Hydroxysuccinimido-2-iminobiotin
Biotinylation of Proteins and Peptides
2-Iminobiotin N-hydroxysuccinimide ester hydrobromide serves as a valuable reagent for the covalent attachment of biotin to primary amine groups found on proteins and peptides. This process is critical for various biochemical assays and for studying protein interactions.
Molecular Biology and Proteomics Research
This compound finds application in molecular biology research, particularly in proteomics, for labelling and immobilising biomolecules. It aids in the analysis of protein structures and functions through biotin-avidin binding systems.
Reagent for Amine Labelling
As a reagent for biotinylating amines, it enables the specific labelling of molecules containing primary amine functionalities. This specificity is crucial for targeted modifications in complex biological samples.
| Molecular weight | 421.31 |
|---|---|
| Empirical formula | C14H20N4O4S · HBr |
| Assay | ~95% (TLC) |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-20/21/22-36/37/38 |
| Safety statements (S) | 53-22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Iminobiotin N-hydroxysuccinimide ester hydrobromide used for?
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This compound is used for biotinylation of proteins and peptides, labelling molecules with primary amine groups, and in molecular biology, proteomics, and protein structural analysis.
What is the CAS number and chemical formula?
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The CAS number is 76939-67-8, and the chemical formula is C14H20N4O4S · HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of approximately 95% (TLC). This is a research-grade chemical and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety considerations for handling this chemical?
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This compound is classified as dangerous. It is harmful if swallowed, in contact with skin, and if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. It is suspected of causing cancer. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 US/P3 EN143), must be used. Handle in a well-ventilated area and seek medical attention if exposed.
How is this chemical supplied and exported by TSS?
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2-Iminobiotin N-hydroxysuccinimide ester hydrobromide is typically stored at -20°C. Tech Serve Solutions is a global supplier and exporter, adhering to all regulations for the safe and compliant shipment of chemicals worldwide.
How can I request a sample or quote?
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To request a sample or a quote for 2-Iminobiotin N-hydroxysuccinimide ester hydrobromide, please contact the Tech Serve Solutions sales department through our website or by phone.
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