3-Bromo-3-methyl-2-(2-nitrophenylthio)-3H-indole

CAS 27933-36-4C15H11BrN2O2SMolecular Biology

3-Bromo-3-methyl-2-(2-nitrophenylthio)-3H-indole (CAS: 27933-36-4) is a chemical compound with the formula C15H11BrN2O2S and a molecular weight of 363.23 g/mol. This reagent is specifically utilised for the chemical cleavage of proteins, with a particular specificity for the carboxyl side of tryptophan residues. It serves as a valuable tool in biochemical research and proteomic studies.

IUPAC: 2-(2-Nitrophenylsulfenyl)-3-methyl-3-bromoindolenine,3-Bromo-3-methyl-2-(2-nitrophenylmercapto)-3H-indole,BNPS-skatol
Synonyms: 2-(2-Nitrophenylsulfenyl)-3-methyl-3-bromoindolenine3-Bromo-3-methyl-2-(2-nitrophenylmercapto)-3H-indoleBNPS-skatol

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3-Bromo-3-methyl-2-(2-nitrophenylthio)-3H-indole (C15H11BrN2O2S) — chemical structure, CAS 27933-36-4; Life Science, fine chemical supplied by Tech Serve Solutions

Mass SpectrometryMolecular BiologyProteomics

01 /Applications

Protein Cleavage Reagent

This compound acts as a specific chemical reagent for cleaving peptide bonds. Its primary application is targeting the carboxyl side of tryptophan residues, enabling controlled fragmentation of proteins for analysis.

Proteomics and Mass Spectrometry

In proteomics, it is used for sample preparation where selective protein fragmentation is required. This aids in downstream analysis by mass spectrometry, allowing for detailed characterisation of protein sequences and modifications.

Molecular Biology Research

Researchers in molecular biology can employ this reagent for specific protein processing. Its targeted cleavage can assist in understanding protein structure-function relationships and in the development of analytical techniques.

02 /Properties

Molecular weight	363.23
Empirical formula	C15H11BrN2O2S
Assay	≥85%
Storage temperature	−20°C
Application	Peptide cleavage reagent specific for the carboxyl side of tryptophan residues.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

27933-36-4

MDL number

MFCD00037978

PubChem substance

24891797

Beilstein registry

1491457

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Bromo-3-methyl-2-(2-nitrophenylthio)-3H-indole used for?

3-Bromo-3-methyl-2-(2-nitrophenylthio)-3H-indole is primarily used as a chemical reagent for the specific cleavage of proteins, particularly at the carboxyl side of tryptophan residues.

What are the CAS number and formula for this compound?

The CAS number is 27933-36-4, and its empirical formula is C15H11BrN2O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of ≥85%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade. It is typically supplied for research and laboratory use.

How should this chemical be handled and stored?

This compound is classified under WGK Germany 3. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and an N95 or P1 respirator filter. It should be stored at −20°C.

Is this product available for export?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product can be packed and shipped internationally according to regulations.

How can I request a quote or sample?

To request a quote or sample, please contact our sales team through the website or by phone. Provide the product name or CAS number for prompt service.