2-Fluorophenyl methyl sulfone
2-Fluorophenyl methyl sulfone (CAS: 654-47-7), with the molecular formula C7H7FO2S and a molecular weight of 174.19 g/mol, is a fluorinated organic building block. This sulfone derivative is utilised in chemical synthesis for the introduction of fluorinated aryl moieties. It serves as a versatile intermediate in the development of diverse chemical entities, particularly within the pharmaceutical and agrochemical sectors. TSS supplies this compound with a minimum assay of 97%.
- IUPAC
- 1-Fluoro-2-(methylsulfonyl)benzene
- Synonyms
- 1-Fluoro-2-(methylsulfonyl)benzene

Organic Synthesis Intermediate
2-Fluorophenyl methyl sulfone functions as a key intermediate in organic synthesis. Its structure allows for participation in various coupling reactions and nucleophilic substitution processes, facilitating the construction of more complex molecules.
Fluorinated Building Block
As a fluorinated aromatic compound, it is valuable in medicinal chemistry and materials science for incorporating fluorine atoms, which can modulate pharmacokinetic properties or enhance material performance.
Pharmaceutical Research
This sulfone is employed in the discovery and development of novel pharmaceutical agents. The presence of the fluorine atom and the sulfone group can influence biological activity and metabolic stability.
Agrochemical Development
It can be used as a precursor in the synthesis of new agrochemicals, where fluorination often plays a role in enhancing efficacy or modifying environmental persistence.
| Molecular weight | 174.19 |
|---|---|
| Empirical formula | C7H7FO2S |
| Assay | 97% |
| Melting point | 48-52 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorophenyl methyl sulfone used for?
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2-Fluorophenyl methyl sulfone is primarily used as a building block in organic synthesis, particularly for introducing fluorinated aryl groups in the development of pharmaceuticals, agrochemicals, and other fine chemicals.
What are the CAS number and formula for 2-Fluorophenyl methyl sulfone?
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The CAS number for 2-Fluorophenyl methyl sulfone is 654-47-7, and its empirical formula is C7H7FO2S.
What grade and purity does Tech Serve Solutions supply for 2-Fluorophenyl methyl sulfone?
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Tech Serve Solutions supplies 2-Fluorophenyl methyl sulfone with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 2-Fluorophenyl methyl sulfone?
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2-Fluorophenyl methyl sulfone is classified as dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, must be worn. Handle in a well-ventilated area.
Is 2-Fluorophenyl methyl sulfone available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Fluorophenyl methyl sulfone, and can facilitate international shipments.
How can I request a sample or quote for 2-Fluorophenyl methyl sulfone?
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To request a sample or a quotation for 2-Fluorophenyl methyl sulfone, please contact our sales team via the website or provided contact details, specifying the quantity required.
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