2-Bromo-1,4-dimethylbenzene
2-Bromo-1,4-dimethylbenzene (CAS 553-94-6) is a halogenated aromatic hydrocarbon with the molecular formula (CH3)2C6H3Br and a molar mass of 185.06 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the formation of complex organic molecules. It is supplied by TSS with a minimum assay of 99%, suitable for various chemical research and development applications.
- IUPAC
- 2-Bromo-p-xylene
- Synonyms
- (CH3)2C6H3Br2-Bromo-p-xylene
Synthesis of Biphenyl Derivatives
2-Bromo-1,4-dimethylbenzene has been utilised in the Yamamoto coupling reaction for the synthesis of 2,5,2′,5′-tetramethylbiphenyl, a key step in creating specific biaryl structures.
Preparation of Isocoumarin Compounds
This brominated xylene derivative is employed in the synthesis of complex heterocyclic compounds, such as cis-3,4-diphenyl-5,8-dimethylisocoumarins, contributing to the development of novel chemical entities.
Organic Building Block
As a versatile aryl halide, 2-Bromo-1,4-dimethylbenzene functions as a foundational component in various organic synthesis pathways, enabling the construction of more elaborate molecular architectures.
| Molecular weight | 185.06 |
|---|---|
| Linear formula | (CH3)2C6H3Br |
| Assay | 99% |
| Boiling point | 199-201 °C(lit.) |
| Density | 1.34 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.550(lit.) |
| Application | 2-Bromo-1,4-dimethylbenzene was used in the synthesis of 2,5,2′,5′-tetrakismethylbiphenyl via Yamamoto coupling reaction1. It was also used in the synthesis of cis-3,4-diphenyl-5,8-dimethylisocoumarins2. |
| Melting point | 9-10 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-1,4-dimethylbenzene used for?
+
2-Bromo-1,4-dimethylbenzene is primarily used as a building block in organic synthesis, including applications like the synthesis of 2,5,2′,5′-tetramethylbiphenyl and cis-3,4-diphenyl-5,8-dimethylisocoumarins.
What are the CAS number and molecular formula for 2-Bromo-1,4-dimethylbenzene?
+
The CAS number for 2-Bromo-1,4-dimethylbenzene is 553-94-6, and its linear formula is (CH3)2C6H3Br.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Bromo-1,4-dimethylbenzene with a minimum assay of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
What are the primary safety concerns when handling 2-Bromo-1,4-dimethylbenzene?
+
2-Bromo-1,4-dimethylbenzene is classified with a Warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, and adequate ventilation are essential when handling this compound.
How is 2-Bromo-1,4-dimethylbenzene packed, shipped, and exported?
+
2-Bromo-1,4-dimethylbenzene is carefully packed to ensure integrity during transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2-Bromo-1,4-dimethylbenzene?
+
To request a sample or a quotation for 2-Bromo-1,4-dimethylbenzene, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis