2-Fluorophenylboronic acid
2-Fluorophenylboronic acid (CAS: 1993-03-9, Formula: FC6H4B(OH)2, MW: 139.92) is a versatile aryl boronic acid derivative supplied by Tech Serve Solutions. This organoboron compound serves as a key reactant in various organic synthesis pathways, particularly in cross-coupling reactions and the preparation of complex molecules. It is valued for its role in the precise construction of novel chemical entities across multiple research and development sectors.
- IUPAC
- 2-Fluorobenzeneboronic acid,o-fluoro-benzeneboronic acid
- Synonyms
- 2-Fluorobenzeneboronic acido-fluoro-benzeneboronic acid
Anion Receptor Synthesis
Used as a reactant for the preparation of phenylboronic catechol esters, which are promising anion receptors for applications in polymer electrolytes. This highlights its utility in advanced materials science.
Asymmetric Synthesis of Alcohols
Serves as a key reagent in the diastereoselective synthesis of trisubstituted allylic alcohols through rhodium-catalyzed arylation reactions, enabling precise stereochemical control.
Suzuki-Miyaura Coupling
Facilitates site-selective Suzuki-Miyaura arylation reactions, a fundamental tool for carbon-carbon bond formation in organic chemistry. This reaction is widely employed in pharmaceutical synthesis.
Addition Reactions
Acts as a substrate in Rh-catalyzed enantioselective addition reactions, contributing to the synthesis of chiral molecules with high optical purity.
Substitution Reactions
Employed in rhodium- and palladium-catalyzed substitution reactions, demonstrating its broad applicability in organometallic chemistry and synthetic methodology development.
| Molecular weight | 139.92 |
|---|---|
| Linear formula | FC6H4B(OH)2 |
| Application | Reactant for:• Preparation of phenylboronic catechol esters as promising anion receptors for polymer electrolytes1• Diastereoselective synthesis of trisubstituted allylic alcohols via rhodium-catalyzed arylation2• Site-selective Suzuki-Miyaura arylation reactions3• Rh-catalyzed enantioselective addition reactions4• Rhodium- and Palladium-catalyzed substitution reactions5 |
| Melting point | 101-110 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorophenylboronic acid used for?
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2-Fluorophenylboronic acid is used as a reactant in various organic synthesis applications, including the preparation of anion receptors, diastereoselective synthesis of allylic alcohols, site-selective Suzuki-Miyaura arylation, and enantioselective addition and substitution reactions.
What is the CAS number and formula for 2-Fluorophenylboronic acid?
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The CAS number for 2-Fluorophenylboronic acid is 1993-03-9, and its linear formula is FC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2-Fluorophenylboronic acid?
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Tech Serve Solutions supplies 2-Fluorophenylboronic acid as a research/technical grade chemical. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise in the product specifications.
How should 2-Fluorophenylboronic acid be handled safely?
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When handling 2-Fluorophenylboronic acid, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the Safety Data Sheet for comprehensive handling information.
Is 2-Fluorophenylboronic acid a controlled substance?
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Based on the provided data, 2-Fluorophenylboronic acid is not indicated as a controlled substance.
How is 2-Fluorophenylboronic acid shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents. 2-Fluorophenylboronic acid is carefully packaged and shipped according to international regulations for chemical transport.
How can I request a sample or quote for 2-Fluorophenylboronic acid?
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To request a sample or a quotation for 2-Fluorophenylboronic acid, please contact our sales team through the TSS website or via direct inquiry.
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