2-Chloro-6-fluorobenzyl chloride
2-Chloro-6-fluorobenzyl chloride (CAS: 55117-15-2), with the molecular formula ClC6H3(F)CH2Cl and a molecular weight of 179.02 g/mol, is a halogenated aromatic compound. It serves as a valuable intermediate and alkylating reagent in organic synthesis. Its primary applications include the preparation of substituted triazoles, 9-substituted adenine derivatives, and the synthesis of the anticoccidial agent aprinocid. Supplied by Tech Serve Solutions with an assay of 98%.
- IUPAC
- 2,α-Dichloro-6-fluorotoluene
Synthesis of Triazole Derivatives
2-Chloro-6-fluorobenzyl chloride is employed as an alkylating agent in the synthesis of 3-benzylsulfanyl derivatives of 1,2,4-triazole and its 4-methyl analogue, facilitating the creation of novel heterocyclic compounds.
Preparation of Adenine Derivatives
This compound is utilised in the preparation of 2-chloro-6-fluorobenzylamine, a crucial precursor for the synthesis of 9-substituted adenine, which are important in medicinal chemistry research.
Aprinocid Synthesis
It serves as a key reactant in the preparation of aprinocid, an anticoccidial agent, through its reaction with adenine, highlighting its role in veterinary pharmaceutical synthesis.
| Molecular weight | 179.02 |
|---|---|
| Linear formula | ClC6H3(F)CH2Cl |
| Assay | 98% |
| Density | 1.401 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.537(lit.) |
| Application | 2-Chloro-6-fluorobenzyl chloride was used:• as alkylating reagent during the synthesis of 3-benzylsulfanyl derivatives of 1,2,4-triazole and 4-methyl-1,2,4-triazole1• in the preparataion of 2-chloro-6-fluorobenzylamine, required for the synthesis of 9-substituted adenine2• in the preparation of aprinocid via reaction with adenine3 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluorobenzyl chloride used for?
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2-Chloro-6-fluorobenzyl chloride is used as an alkylating reagent in organic synthesis, particularly in the preparation of substituted triazoles, 9-substituted adenine derivatives, and the anticoccidial agent aprinocid.
What are the CAS number and formula for 2-Chloro-6-fluorobenzyl chloride?
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The CAS number is 55117-15-2 and the linear formula is ClC6H3(F)CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-6-fluorobenzyl chloride with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 2-Chloro-6-fluorobenzyl chloride be handled safely?
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2-Chloro-6-fluorobenzyl chloride is classified as Dangerous (Danger) and causes severe skin burns and eye damage (H314). Handling requires full personal protective equipment, including a full-face respirator, gloves, and goggles. Ensure adequate ventilation and consult the Safety Data Sheet before use.
How is 2-Chloro-6-fluorobenzyl chloride packed, shipped, and exported?
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2-Chloro-6-fluorobenzyl chloride is packed according to UN 3265, Class 8, Packing Group II regulations. Tech Serve Solutions handles global export, ensuring compliance with all shipping and safety regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloro-6-fluorobenzyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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