3,4-Dimethoxy-4′-fluorochalcone
3,4-Dimethoxy-4′-fluorochalcone (CAS 28081-14-3) is a specialised organic compound with the linear formula (CH3O)2C6H3CH=CHCOC6H4F and a molecular weight of 286.30 g/mol. This fluorinated chalcone derivative serves as a valuable building block in organic synthesis. Its structure, featuring both methoxy and fluoro substituents, makes it useful for constructing more complex molecules, particularly in the fields of chemical research and development, and potentially in the early stages of pharmaceutical discovery.
- Synonyms
- (CH3O)2C6H3CH=CHCOC6H4F

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its chalcone backbone and specific functional groups allow for diverse chemical transformations.
Research and Development
Employed in academic and industrial research settings for exploring novel chemical pathways and developing new compounds with potential biological or material properties.
Building Block for Heterocycles
Can serve as a precursor for the synthesis of various heterocyclic compounds, which are important scaffolds in medicinal chemistry.
| Molecular weight | 286.30 |
|---|---|
| Linear formula | (CH3O)2C6H3CH=CHCOC6H4F |
| Assay | 97% |
| Melting point | 90-93 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxy-4′-fluorochalcone used for?
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3,4-Dimethoxy-4′-fluorochalcone is primarily used as a building block and intermediate in organic synthesis for research and development purposes, including the potential synthesis of novel heterocyclic compounds.
What are the CAS number and formula for 3,4-Dimethoxy-4′-fluorochalcone?
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The CAS number is 28081-14-3, and its linear formula is (CH3O)2C6H3CH=CHCOC6H4F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxy-4′-fluorochalcone with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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Users should wear eyeshields and gloves, and use a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is 3,4-Dimethoxy-4′-fluorochalcone packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and shipping protocols are followed for all its chemical products.
How can I request a quote or sample for 3,4-Dimethoxy-4′-fluorochalcone?
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Please contact our sales team via the website or phone to request a quote or a sample of 3,4-Dimethoxy-4′-fluorochalcone.
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