3,4-Dimethoxy-3-cyclobutene-1,2-dione
3,4-Dimethoxy-3-cyclobutene-1,2-dione (CAS 5222-73-1), also known as Dimethyl squarate, is a versatile organic building block with a molecular weight of 142.11. This compound serves as a crucial starting material in organic synthesis, particularly for the preparation of o-quinodimethanes, benzocyclobutenes, and various quinone derivatives. Its unique structure makes it valuable for researchers and chemists engaged in complex molecular construction.
- IUPAC
- Dimethyl squarate
- Synonyms
- 5222-73-1(CH3O)2C4(=O)2Dimethyl squarate
Precursor for o-Quinodimethanes
3,4-Dimethoxy-3-cyclobutene-1,2-dione is utilised as a starting material in the synthesis of o-quinodimethanes, which are reactive intermediates in Diels-Alder reactions and other cycloadditions.
Synthesis of Benzocyclobutenes
This dione is employed in the preparation of benzocyclobutene derivatives, a class of compounds with applications in materials science and medicinal chemistry.
Generation of Quinone Structures
The compound serves as a precursor for the synthesis of various quinone structures, which are important motifs in natural products and pharmaceuticals.
| Molecular weight | 142.11 |
|---|---|
| Linear formula | (CH3O)2C4(=O)2 |
| Assay | 99% |
| Storage temperature | 2-8°C |
| Application | Starting material used to prepare o-quinodimethanes,1 benzocyclobutenes,1 and quinones.2,3 |
| Melting point | 55-57 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 42/43 |
| Safety statements (S) | 22-24/25-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxy-3-cyclobutene-1,2-dione used for?
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3,4-Dimethoxy-3-cyclobutene-1,2-dione is used as a starting material for the preparation of o-quinodimethanes, benzocyclobutenes, and quinones.
What is the CAS number and formula for 3,4-Dimethoxy-3-cyclobutene-1,2-dione?
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The CAS number is 5222-73-1 and the linear formula is (CH3O)2C4(=O)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxy-3-cyclobutene-1,2-dione with a minimum purity of 99%. This is a technical/research grade material; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,4-Dimethoxy-3-cyclobutene-1,2-dione be handled safely?
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Due to hazards including skin sensitisation and respiratory sensitisation (H317, H334), it is essential to avoid breathing dust and contact with skin and eyes. Use a dust mask type N95 (US), wear eyeshields, faceshields, and gloves. Ensure adequate ventilation.
Is this compound available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,4-Dimethoxy-3-cyclobutene-1,2-dione.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 3,4-Dimethoxy-3-cyclobutene-1,2-dione.
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