2-Chloro-6-fluorobenzyl bromide
2-Chloro-6-fluorobenzyl bromide (CAS: 68220-26-8), with the molecular formula ClC6H3(F)CH2Br and a molecular weight of 223.47 g/mol, is a halogenated aromatic compound. It functions as a versatile building block in organic synthesis, particularly for introducing the 2-chloro-6-fluorobenzyl moiety into various molecular structures. Its reactivity makes it valuable in the development of pharmaceuticals and agrochemicals.
Pharmaceutical Intermediate
This compound serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). It enables the precise introduction of the 2-chloro-6-fluorobenzyl group, a structural feature found in certain drug candidates.
Agrochemical Synthesis
In the agrochemical industry, 2-Chloro-6-fluorobenzyl bromide is utilised as a building block for creating novel pesticides, herbicides, and fungicides. Its specific chemical structure can contribute to the efficacy and target specificity of these agricultural products.
Organic Synthesis Reagent
As a halogenated benzyl bromide derivative, it is employed in general organic synthesis for C-alkylation reactions. The presence of both chlorine and fluorine atoms on the aromatic ring offers unique reactivity and potential for further functionalisation.
| Molecular weight | 223.47 |
|---|---|
| Linear formula | ClC6H3(F)CH2Br |
| Assay | 96% |
| Density | 1.629 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.568(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluorobenzyl bromide primarily used for?
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2-Chloro-6-fluorobenzyl bromide is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 2-Chloro-6-fluorobenzyl bromide?
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The CAS number for 2-Chloro-6-fluorobenzyl bromide is 68220-26-8, and its molecular formula is ClC6H3(F)CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-6-fluorobenzyl bromide with a minimum assay of 96%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 2-Chloro-6-fluorobenzyl bromide be handled safely?
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Handle 2-Chloro-6-fluorobenzyl bromide with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. It is a warning hazard that may cause skin, eye, and respiratory irritation (H315, H319, H335).
Is 2-Chloro-6-fluorobenzyl bromide typically exported?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Chloro-6-fluorobenzyl bromide, which is shipped worldwide.
How can I request a quote or sample for 2-Chloro-6-fluorobenzyl bromide?
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To request a quote or sample of 2-Chloro-6-fluorobenzyl bromide, please contact our sales team through the website or by phone, providing your specific requirements.
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