2-Chloro-5-nitrobenzaldehyde
2-Chloro-5-nitrobenzaldehyde (CAS 6361-21-3; Formula: ClC6H3(NO2)CHO; Molar Mass: 185.56 g/mol) is a chemical intermediate. It is a substituted benzaldehyde, featuring both a chlorine atom and a nitro group on the aromatic ring, alongside the aldehyde functionality. This unique structure makes it valuable in organic synthesis, particularly as a building block for more complex molecules in the pharmaceutical and chemical industries.

Intermediate in Organic Synthesis
This compound serves as a key building block in the synthesis of various organic molecules. Its reactive aldehyde group and substituted aromatic ring allow for diverse chemical transformations.
Pharmaceutical Intermediate
2-Chloro-5-nitrobenzaldehyde is utilised in the multi-step synthesis pathways for active pharmaceutical ingredients (APIs). Its specific functional groups enable the construction of complex heterocyclic systems often found in drug molecules.
Research and Development
Used in academic and industrial research laboratories for exploring new synthetic routes and developing novel compounds. Its availability as a fine chemical supports R&D efforts in materials science and medicinal chemistry.
| Molecular weight | 185.56 |
|---|---|
| Linear formula | ClC6H3(NO2)CHO |
| Assay | 97% |
| Application | 2-Chloro-5-nitrobenzaldehyde was used in the synthesis of 5-nitro-2-(1H-pyrrol-1-yl)benzaldehyde1. |
| Melting point | 75-77 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-nitrobenzaldehyde used for?
+
2-Chloro-5-nitrobenzaldehyde is primarily used as a building block in organic synthesis, including the preparation of pharmaceutical intermediates and other fine chemicals. It was used in the synthesis of 5-nitro-2-(1H-pyrrol-1-yl)benzaldehyde.
What is the CAS number and chemical formula for 2-Chloro-5-nitrobenzaldehyde?
+
The CAS number is 6361-21-3, and the linear chemical formula is ClC6H3(NO2)CHO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Chloro-5-nitrobenzaldehyde with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 2-Chloro-5-nitrobenzaldehyde?
+
Handle with care. This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 2, indicating it is hazardous to water.
Is 2-Chloro-5-nitrobenzaldehyde a controlled substance?
+
The provided data does not indicate that 2-Chloro-5-nitrobenzaldehyde is a controlled substance.
How is 2-Chloro-5-nitrobenzaldehyde exported and shipped?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. Please contact us for specific shipping and export details regarding 2-Chloro-5-nitrobenzaldehyde.
How can I request a sample or quote for 2-Chloro-5-nitrobenzaldehyde?
+
To request a sample or a quotation for 2-Chloro-5-nitrobenzaldehyde, please use the contact form on our website or call our sales department.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis