2-Chloro-5-nitrobenzophenone
2-Chloro-5-nitrobenzophenone (CAS: 34052-37-4) is a chemical compound with the formula ClC6H3(NO2)COC6H5 and a molecular weight of 261.66 g/mol. This ketone serves as a valuable building block in organic synthesis. It is primarily utilised in the creation of advanced materials, such as sulfone-activated difluoro monomers and in the derivatisation of phenols for isotopic labelling studies. Available at 98% purity, it is supplied by Tech Serve Solutions for research and chemical manufacturing purposes.

Synthesis of Difluoro Monomers
2-Chloro-5-nitrobenzophenone has been employed in the synthesis of sulfone-activated difluoro monomers, including bis(2-benzoyl-4-fluorophenyl) sulfone and 2-benzoyl-4,4′-difluorophenyl sulfone.
Isotopic Labelling
This compound is used in the derivatisation of phenols for the preparation of uniformly labelled catechol isotopes, specifically for 13C and 14C labelled compounds.
Organic Building Block
As a ketone and an organic building block, it offers a versatile scaffold for constructing more complex organic molecules in various research and development settings.
| Molecular weight | 261.66 |
|---|---|
| Linear formula | ClC6H3(NO2)COC6H5 |
| Assay | 98% |
| Application | 2-Chloro-5-nitrobenzophenone was used in the synthesis of sulfone-activated difluoro monomers with benzoyl substituents: bis(2-benzoyl-4-fluorophenyl) sulfone and 2-benzoyl-4,4′-difluorophenyl sulfone1.It was used in derivatization of phenols during the synthesis of 13C- and 14C-uniformly labeled catechol2. |
| Melting point | 83-85 °C(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 51/53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-nitrobenzophenone used for?
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2-Chloro-5-nitrobenzophenone is used as a building block in organic synthesis, notably in the preparation of difluoro monomers and for isotopic labelling studies of catechols.
What are the CAS number and chemical formula for 2-Chloro-5-nitrobenzophenone?
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The CAS number is 34052-37-4 and the chemical formula is ClC6H3(NO2)COC6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-nitrobenzophenone with an assay of 98%. This product is not represented as USP, BP, or EP grade and is intended for research and technical applications.
What are the safety and handling recommendations for 2-Chloro-5-nitrobenzophenone?
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2-Chloro-5-nitrobenzophenone is classified with GHS07 symbol and a Warning signal word, indicating it can cause serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields and gloves, and follow precautionary statements P305 + P351 + P338.
Is 2-Chloro-5-nitrobenzophenone safely packed and exported by TSS?
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Yes, Tech Serve Solutions, a specialist global supplier and exporter since 1998, ensures that chemicals like 2-Chloro-5-nitrobenzophenone are appropriately packed and exported according to international regulations, including UN 3077 for transport.
How can I request a sample or quote for 2-Chloro-5-nitrobenzophenone?
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To request a sample or a quote for 2-Chloro-5-nitrobenzophenone, please contact our sales team through the TSS website or by phone.
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