2-Chloro-5-nitrobenzotrifluoride

CAS 777-37-7ClC6H3(NO2)CF3Chemical Synthesis

2-Chloro-5-nitrobenzotrifluoride (CAS: 777-37-7; Formula: ClC6H3(NO2)CF3; MW: 225.55) is a versatile organic building block. This trifluoromethylated and nitrated chlorobenzene derivative is a valuable intermediate in organic synthesis. Its structure allows for diverse chemical transformations, making it a key component in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is offered by TSS with a minimum assay of 97%.

IUPAC: 2-Chloro-5-nitro-α,α,α-trifluorotoluene

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2-Chloro-5-nitrobenzotrifluoride (ClC6H3(NO2)CF3) — chemical structure, CAS 777-37-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisNitro CompoundsNitrogen CompoundsOrganic Building Blocks

01 /Applications

Pharmaceutical Intermediate

2-Chloro-5-nitrobenzotrifluoride serves as a crucial building block in the synthesis of various pharmaceutical active ingredients. Its unique combination of functional groups facilitates the construction of complex molecular scaffolds required for drug discovery and development.

Agrochemical Synthesis

This compound is employed in the development of novel agrochemicals, including pesticides and herbicides. The trifluoromethyl and nitro functionalities can impart specific biological activities and enhance the efficacy of agricultural products.

Organic Synthesis Reagent

As a functionalized aromatic compound, it is utilized in general organic synthesis for creating diverse chemical structures. Its reactivity allows for various substitution and modification reactions, enabling access to a wide range of derivatives.

02 /Properties

Molecular weight	225.55
Linear formula	ClC6H3(NO2)CF3
Assay	97%
Boiling point	108 °C/10 mmHg(lit.)
Density	1.527 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.508(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	99 °C / 210.2 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

777-37-7

MDL number

MFCD00007296

PubChem substance

24892830

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Chloro-5-nitrobenzotrifluoride used for?

2-Chloro-5-nitrobenzotrifluoride is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and agrochemicals.

What are the CAS number and molecular formula?

The CAS number for 2-Chloro-5-nitrobenzotrifluoride is 777-37-7, and its molecular formula is ClC6H3(NO2)CF3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-Chloro-5-nitrobenzotrifluoride with a minimum assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.

What are the primary safety hazards associated with this compound?

This compound is classified as a Warning (GHS07) and may cause harm if swallowed (H302), skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used.

How is 2-Chloro-5-nitrobenzotrifluoride packed and exported?

Tech Serve Solutions carefully packs and exports chemicals in compliance with international shipping regulations. For specific packaging and shipping details, please contact our sales team.

How can I request a quote or sample?

To request a quote or a sample of 2-Chloro-5-nitrobenzotrifluoride, please use the contact form on our website or email our sales department directly.