2-Chloro-5-nitropyridine
2-Chloro-5-nitropyridine (CAS: 4548-45-2), with the molecular formula C5H3ClN2O2 and a molecular weight of 158.54 g/mol, is a key chemical intermediate. It belongs to the class of halogenated heterocyclic compounds, specifically pyridines. This compound serves as a valuable building block in organic synthesis, particularly in the creation of more complex molecules for research and development within the chemical industry.

Synthesis of Heterocyclic Compounds
2-Chloro-5-nitropyridine is utilised as a precursor in the synthesis of various functionalised heterocyclic systems. Its pyridine core with chloro and nitro substituents allows for diverse chemical transformations.
Preparation of Dipyridyl Sulfides
This compound has been employed in specific synthetic pathways, such as the preparation of 5,5′-dinitro-2,2′-dipyridylsulfide. This highlights its utility in crafting molecules with unique structural features.
Chemical Research and Development
As a versatile building block, 2-Chloro-5-nitropyridine finds application in research laboratories for the development of novel compounds and materials. Its reactivity profile makes it a useful reagent in exploratory organic chemistry.
| Molecular weight | 158.54 |
|---|---|
| Empirical formula | C5H3ClN2O2 |
| Assay | ≥97.0% (AT) |
| Grade | purum |
| Application | 2-Chloro-5-nitropyridine has been used in preparation of 5,5′-dinitro-2,2′-dipyridylsulfide1. |
| Melting point | 105-108 °C(lit.)105-109 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-nitropyridine used for?
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2-Chloro-5-nitropyridine is primarily used as a chemical intermediate and building block in organic synthesis, including the preparation of compounds like 5,5′-dinitro-2,2′-dipyridylsulfide.
What is the CAS number and chemical formula for 2-Chloro-5-nitropyridine?
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The CAS number for 2-Chloro-5-nitropyridine is 4548-45-2, and its chemical formula is C5H3ClN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-nitropyridine with a purity of ≥97.0% (AT), graded as purum. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with 2-Chloro-5-nitropyridine?
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2-Chloro-5-nitropyridine is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used during handling.
How is 2-Chloro-5-nitropyridine packed and shipped?
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2-Chloro-5-nitropyridine is carefully packed to ensure safe transit and is available for global export. Specific packaging details can be provided upon request.
How can I request a quote or sample for 2-Chloro-5-nitropyridine?
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To request a quote or a sample of 2-Chloro-5-nitropyridine, please contact our sales team via the website or direct email, providing your requirements and shipping details.
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