2-Chloro-5-nitropyrimidine
2-Chloro-5-nitropyrimidine (CAS: 10320-42-0) is a halogenated heterocyclic organic compound with the molecular formula C4H2ClN3O2 and a molecular weight of 159.53 g/mol. It serves as a valuable building block in organic synthesis, particularly in the pharmaceutical and chemical industries. Its pyrimidine core, functionalised with a chlorine atom and a nitro group, allows for diverse chemical transformations in the development of novel molecules and intermediates.

Pharmaceutical Intermediate
2-Chloro-5-nitropyrimidine is employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure is amenable to nucleophilic substitution and other reactions crucial for building complex drug molecules.
Agrochemical Synthesis
The compound can be utilised in the development of novel agrochemicals, including herbicides and pesticides, owing to its heterocyclic structure which is common in bioactive molecules.
Research and Development
It is frequently used in academic and industrial research laboratories as a versatile building block for exploring new chemical entities and synthetic pathways.
Material Science
The unique electronic properties imparted by the nitro and chloro substituents may find applications in the synthesis of specialised organic materials.
| Molecular weight | 159.53 |
|---|---|
| Empirical formula | C4H2ClN3O2 |
| Assay | 97% |
| Storage temperature | −20°C |
| Melting point | 105-110 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Transport (UN / ADR) | UN 3335 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-nitropyrimidine used for?
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2-Chloro-5-nitropyrimidine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates, agrochemicals, and in chemical research and development.
What is the CAS number and molecular formula for 2-Chloro-5-nitropyrimidine?
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The CAS number is 10320-42-0 and the molecular formula is C4H2ClN3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-nitropyrimidine with a minimum assay of 97%. This product is intended for laboratory and research purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 2-Chloro-5-nitropyrimidine be handled safely?
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2-Chloro-5-nitropyrimidine is a Danger substance. It is harmful if swallowed (H302), causes skin irritation (H315), may cause an allergic skin reaction (H317), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment (P261, P280) and ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is 2-Chloro-5-nitropyrimidine shipped and exported?
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Tech Serve Solutions can expertly pack, ship, and export 2-Chloro-5-nitropyrimidine globally to meet your research and manufacturing needs. Please contact us for specific shipping details.
How can I request a sample or quote for 2-Chloro-5-nitropyrimidine?
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To request a sample or a quote for 2-Chloro-5-nitropyrimidine, please utilise the product inquiry form on our website or contact our sales team directly.
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