2-Chloro-5-methylphenyl isocyanate
2-Chloro-5-methylphenyl isocyanate (CAS: 40398-03-6), with the molecular formula ClC6H3(CH3)NCO and a molecular weight of 167.59 g/mol, is a reactive organic compound. This chemical serves as a valuable building block in organic synthesis, particularly in the preparation of various derivatives. Its isocyanate functionality allows for reactions with nucleophiles, making it a key intermediate in the development of specialised chemical products.
Organic Synthesis Intermediate
2-Chloro-5-methylphenyl isocyanate is primarily employed as a versatile intermediate in the synthesis of more complex organic molecules. Its isocyanate group readily reacts with alcohols, amines, and other nucleophilic species, facilitating the construction of diverse chemical structures.
Pharmaceutical Research and Development
This compound may be utilised in R&D settings for the synthesis of novel pharmaceutical candidates. The introduction of the chloro-methylphenyl moiety can impart specific properties to target molecules, aiding in drug discovery efforts.
Agrochemical Synthesis
The isocyanate functionality makes it suitable for use in the synthesis of certain agrochemical compounds. It can be incorporated into molecules designed for crop protection or other agricultural applications.
| Molecular weight | 167.59 |
|---|---|
| Linear formula | ClC6H3(CH3)NCO |
| Assay | 98% |
| Melting point | 39-42 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-methylphenyl isocyanate used for?
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2-Chloro-5-methylphenyl isocyanate is primarily used as a building block in organic synthesis and potentially in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula?
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The CAS number for 2-Chloro-5-methylphenyl isocyanate is 40398-03-6, and its molecular formula is ClC6H3(CH3)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-methylphenyl isocyanate with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified with GHS07 and GHS08 symbols and carries a Danger signal word. It is harmful if swallowed, in contact with skin, or if inhaled, causes skin irritation, serious eye irritation, and may cause respiratory irritation and an allergic reaction in the case of inhalation. Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, must be used.
How is 2-Chloro-5-methylphenyl isocyanate packed, shipped, and exported?
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Tech Serve Solutions ensures secure packaging suitable for chemical transport and offers global export services for this product.
How can I request a sample or quote for 2-Chloro-5-methylphenyl isocyanate?
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Please contact our sales team via the website or direct enquiry for sample or quotation requests.
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