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2-Chloro-5-nitroaniline

CAS 6283-25-6ClC6H3(NO2)NH2Chemical Synthesis

2-Chloro-5-nitroaniline (CAS: 6283-25-6), with the molecular formula ClC6H3(NO2)NH2 and a molar mass of 172.57 g/mol, is a fine chemical intermediate. It serves as a crucial building block in organic synthesis, particularly for the production of dyes, pigments, and pharmaceutical intermediates. Its distinct chemical structure, featuring both an amine and a nitro group on a chlorinated benzene ring, allows for diverse chemical transformations. TSS supplies this compound with an assay of 98%.

IUPAC
2-Amino-1-chloro-4-nitrobenzene
Synonyms
2-Amino-1-chloro-4-nitrobenzene
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2-Chloro-5-nitroaniline (ClC6H3(NO2)NH2) — chemical structure, CAS 6283-25-6; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisNitrogen Compounds
01 /Applications

Dye and Pigment Synthesis

2-Chloro-5-nitroaniline is a key intermediate in the synthesis of various azo dyes and pigments. Its functional groups enable coupling reactions essential for creating vibrant and stable colourants used in textiles, inks, and plastics.

Pharmaceutical Intermediate

This compound serves as a valuable building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its structure can be modified to introduce specific functionalities required for therapeutic agents.

Organic Synthesis Reagent

As a versatile organic building block, 2-Chloro-5-nitroaniline is employed in diverse chemical research and development projects. It facilitates the creation of complex organic molecules through various synthetic pathways.

02 /Properties
Molecular weight172.57
Linear formulaClC6H3(NO2)NH2
Assay98%
Melting point118-120 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H300Fatal if swallowed
  • H310Fatal in contact with skin
  • H330Fatal if inhaled
  • H373May cause damage to organs through prolonged exposure
  • H411Toxic to aquatic life with long-lasting effects

Precautionary statements

  • P260Do not breathe dust, fume, gas, mist, vapours or spray
  • P264Wash thoroughly after handling
  • P273Avoid release to the environment
  • P280Wear protective gloves, clothing and eye/face protection
  • P284Wear respiratory protection
  • P301IF SWALLOWED
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2237 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)T+,N
Risk statements (R)26/27/28-33-51/53
Safety statements (S)28-36/37-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
6283-25-6
MDL number
MFCD00007668
PubChem substance
24892808
Beilstein registry
2208878
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Chloro-5-nitroaniline used for?

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2-Chloro-5-nitroaniline (CAS: 6283-25-6) is primarily used as a building block in organic synthesis, including the production of dyes, pigments, and pharmaceutical intermediates.

What is the CAS number and chemical formula for 2-Chloro-5-nitroaniline?

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The CAS number is 6283-25-6 and the chemical formula is ClC6H3(NO2)NH2.

What grade and purity does Tech Serve Solutions supply for 2-Chloro-5-nitroaniline?

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Tech Serve Solutions supplies 2-Chloro-5-nitroaniline with a purity of 98%. TSS does not represent this product as USP, BP, or EP grade; it is supplied for technical and research purposes.

How is 2-Chloro-5-nitroaniline handled and what are the associated hazards?

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2-Chloro-5-nitroaniline is classified with the GHS symbols GHS06, GHS08, and GHS09, carrying a Danger signal word. It is acutely toxic if swallowed, in contact with skin, or if inhaled (H300, H310, H330), may cause damage to organs through prolonged or repeated exposure (H373), and is toxic to aquatic life with long-lasting effects (H411). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filter), must be used.

How is 2-Chloro-5-nitroaniline packed, shipped, and exported?

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2-Chloro-5-nitroaniline is packed in compliance with international shipping regulations. It is exported globally by Tech Serve Solutions, a specialist supplier with extensive experience in handling hazardous chemicals.

How can I request a sample or quote for 2-Chloro-5-nitroaniline?

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To request a sample or a quote for 2-Chloro-5-nitroaniline, please contact the Tech Serve Solutions sales team through the website's inquiry form or by direct telephone. Specify the CAS number 6283-25-6 for prompt service.

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