2-Chloro-5-methylpyridine
2-Chloro-5-methylpyridine (CAS: 18368-64-4), with the molecular formula C6H6ClN and a molecular weight of 127.57 g/mol, is a halogenated pyridine derivative. It is a key intermediate in organic synthesis, particularly valuable in the preparation of more complex heterocyclic compounds. This chemical serves as a versatile building block in research and development, facilitating the creation of novel molecules for various chemical applications.

Organic Synthesis Intermediate
Serves as a crucial building block for the synthesis of diverse organic molecules, including pharmaceuticals and agrochemicals. Its reactive chlorine atom allows for various functionalisation reactions.
Heterocyclic Chemistry
A valuable reagent in heterocyclic chemistry for constructing substituted pyridine rings. These structures are prevalent in many biologically active compounds.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic routes and developing novel compounds with potential therapeutic or material science applications.
| Molecular weight | 127.57 |
|---|---|
| Empirical formula | C6H6ClN |
| Assay | 97% |
| Boiling point | 97 °C/30 mmHg(lit.) |
| Density | 1.169 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.53(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-38-52/53 |
| Safety statements (S) | 23-25-36/37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-methylpyridine used for?
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2-Chloro-5-methylpyridine (CAS: 18368-64-4) is primarily used as an intermediate in organic synthesis, particularly for building heterocyclic compounds relevant to pharmaceuticals and agrochemicals, and in general chemical research and development.
What are the CAS number and formula for 2-Chloro-5-methylpyridine?
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The CAS number is 18368-64-4, and the empirical formula is C6H6ClN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-methylpyridine with an assay of 97%. This product is intended for laboratory and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 2-Chloro-5-methylpyridine be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields, face shields, and gloves. Ensure adequate ventilation, using a suitable respirator filter (e.g., type ABEK) if necessary. Avoid ingestion and skin contact, as it is harmful if swallowed and in contact with skin, and causes skin irritation. Prevent release to the environment, as it is harmful to aquatic life with long-lasting effects.
Is 2-Chloro-5-methylpyridine a controlled substance?
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The provided safety data does not indicate that 2-Chloro-5-methylpyridine (CAS: 18368-64-4) is a controlled substance.
How is 2-Chloro-5-methylpyridine packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing and adherence to all regulations for shipping chemicals worldwide.
How can I request a quote or sample for 2-Chloro-5-methylpyridine?
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Please contact the Tech Serve Solutions sales team via our website or direct inquiry to request a quote or a sample of 2-Chloro-5-methylpyridine (CAS: 18368-64-4).
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