Benzo-1,4-dioxane
Benzo-1,4-dioxane (CAS 493-09-4), with the molecular formula C8H8O2 and a molecular weight of 136.15 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis. Its primary known application involves its use in the preparation of stereoisomers that have been investigated for their potential as alpha- and beta-adrenergic antagonists, contributing to research in medicinal chemistry.
- IUPAC
- 1,2-Ethylenedioxybenzene,1,4-Benzodioxan,2,3-Dihydro-1,4-benzodioxin
- Synonyms
- 1,4-Benzodioxan2,3-Dihydro-1,4-benzodioxin1,2-Ethylenedioxybenzene
Synthesis of Adrenergic Antagonists
Benzo-1,4-dioxane has been employed in the synthesis of stereoisomers evaluated for their activity as alpha- and beta-adrenergic antagonists. This application highlights its role in pharmaceutical research and development.
Heterocyclic Building Block
As a benzodioxane derivative, it functions as a versatile building block in organic synthesis. Its structure allows for further chemical modifications to create more complex molecules for various research purposes.
Chemical Synthesis Intermediate
This compound is utilized in diverse chemical synthesis pathways. Researchers and chemists can leverage Benzo-1,4-dioxane as an intermediate to construct novel organic compounds.
| Molecular weight | 136.15 |
|---|---|
| Empirical formula | C8H8O2 |
| Assay | 97% |
| Boiling point | 103 °C/6 mmHg(lit.) |
| Density | 1.142 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.549(lit.) |
| Application | Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) was used in the synthesis of stereoisomers which were evaluated as α- and β- adrenergic antagonists1. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzo-1,4-dioxane used for?
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Benzo-1,4-dioxane is primarily used as a building block in chemical synthesis, notably in the preparation of stereoisomers investigated as alpha- and beta-adrenergic antagonists.
What is the CAS number and formula for Benzo-1,4-dioxane?
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The CAS number for Benzo-1,4-dioxane is 493-09-4, and its empirical formula is C8H8O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzo-1,4-dioxane with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Benzo-1,4-dioxane?
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Benzo-1,4-dioxane has a flash point of 69 °C (156.2 °F). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (half-mask respirator or multi-purpose combination cartridge), should be used when handling this chemical. Please consult the Safety Data Sheet for comprehensive safety information.
How is Benzo-1,4-dioxane packed, shipped, and exported?
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Tech Serve Solutions securely packs and ships chemicals according to international regulations. We offer global export services for Benzo-1,4-dioxane.
How can I request a quote or sample?
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To request a quote or a sample of Benzo-1,4-dioxane, please contact our sales team through the provided channels on our website.
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