2-Chloro-5-fluoropyrimidine
2-Chloro-5-fluoropyrimidine (CAS: 62802-42-0) is a halogenated heterocyclic building block with the molecular formula C4H2ClFN2 and a molecular weight of 132.52 g/mol. It is primarily utilised in chemical synthesis as a precursor for more complex fluorinated organic compounds. Its structure, featuring both chlorine and fluorine substituents on a pyrimidine ring, makes it a valuable intermediate in the development of novel molecules for research and industrial applications, particularly within the pharmaceutical and agrochemical sectors.
Fluorinated Heterocycle Synthesis
2-Chloro-5-fluoropyrimidine serves as a key building block for constructing advanced fluorinated heterocyclic compounds. Its reactive sites allow for diverse synthetic modifications, enabling the creation of specialised molecules.
Pharmaceutical Intermediate
This compound is employed in the synthesis pathways of various pharmaceutical intermediates and active pharmaceutical ingredients (APIs). The introduction of fluorine can significantly modulate the pharmacokinetic properties of drug candidates.
Agrochemical Research
It finds application in the development of new agrochemicals, where fluorinated heterocycles are often incorporated to enhance efficacy and stability.
Material Science
The unique electronic properties imparted by the fluoro-pyrimidine moiety can be advantageous in the design of functional materials.
| Molecular weight | 132.52 |
|---|---|
| Empirical formula | C4H2ClFN2 |
| Assay | 97% |
| Density | 1.073 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.503(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 65 °C / 149 °F |
| Transport (UN / ADR) | UN 3267 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-fluoropyrimidine used for?
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2-Chloro-5-fluoropyrimidine is primarily used as a building block in chemical synthesis, particularly for developing fluorinated heterocyclic compounds relevant to the pharmaceutical and agrochemical industries.
What is the CAS number and formula for 2-Chloro-5-fluoropyrimidine?
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The CAS number is 62802-42-0 and the empirical formula is C4H2ClFN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-fluoropyrimidine with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations for handling 2-Chloro-5-fluoropyrimidine?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Appropriate personal protective equipment, including gloves, goggles, a face shield, and a suitable respirator, is essential. Handle only in a well-ventilated area.
Can Tech Serve Solutions export 2-Chloro-5-fluoropyrimidine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-5-fluoropyrimidine.
How can I request a quote or sample for 2-Chloro-5-fluoropyrimidine?
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To request a quote or sample, please contact our sales team through the website or by telephone, providing your specific requirements.
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