2-Chloro-5-fluoronitrobenzene
2-Chloro-5-fluoronitrobenzene (CAS: 345-17-5, Formula: ClC6H3(F)NO2) is a chemical intermediate with a molecular weight of 175.54 g/mol. This fluorinated aromatic compound serves as a versatile building block in organic synthesis. It is primarily utilised in the development of pharmaceuticals, agrochemicals, and specialty materials, owing to its specific substitution pattern which allows for targeted chemical transformations. Tech Serve Solutions supplies this compound for research and industrial applications.

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its structure is valuable for introducing specific functionalities into complex molecules.
Agrochemical Development
Serves as a precursor in the manufacturing of pesticides, herbicides, and fungicides. The presence of fluorine and chlorine can enhance the biological activity of agrochemical compounds.
Organic Synthesis Building Block
A versatile reagent for creating more complex organic molecules. It is particularly useful in reactions involving nucleophilic aromatic substitution and reduction of the nitro group.
Materials Science
Incorporated into the synthesis of advanced materials and dyes. The unique electronic properties conferred by the nitro and halogen groups are beneficial in these applications.
| Molecular weight | 175.54 |
|---|---|
| Linear formula | ClC6H3(F)NO2 |
| Assay | 99% |
| Boiling point | 238 °C(lit.) |
| Melting point | 37-40 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-fluoronitrobenzene used for?
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2-Chloro-5-fluoronitrobenzene is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It functions as a versatile building block in chemical research and development.
What are the CAS number and chemical formula for 2-Chloro-5-fluoronitrobenzene?
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The CAS number for 2-Chloro-5-fluoronitrobenzene is 345-17-5, and its chemical formula is ClC6H3(F)NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-fluoronitrobenzene with an assay of 99%. This product is supplied for research and industrial use and is not represented as USP, BP, or EP grade.
How should 2-Chloro-5-fluoronitrobenzene be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (NIOSH N95 type). Avoid inhalation of dust and vapour, and prevent contact with skin and eyes. It is classified with GHS07 symbol and carries a Warning signal word, with hazards including H302, H312, H315, H319, H332, and H335.
Is 2-Chloro-5-fluoronitrobenzene exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-5-fluoronitrobenzene, serving customers worldwide.
How can I request a quote or sample for 2-Chloro-5-fluoronitrobenzene?
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To request a quote or sample, please contact our sales team via the website or direct telephone inquiry. Our team will assist you with your specific requirements.
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