2-Chloro-5-fluoropyridine-3-carboxylic acid
2-Chloro-5-fluoropyridine-3-carboxylic acid (CAS: 38186-88-8) is a halogenated heterocyclic building block with the molecular formula C6H3ClFNO2 and a molecular weight of 175.54 g/mol. This pyridine derivative is valuable in organic synthesis, particularly for the introduction of fluorinated pyridine moieties into more complex molecules. It serves as a key intermediate in the development of pharmaceuticals and agrochemicals due to the unique electronic and steric properties conferred by the fluorine and chlorine substituents.
- IUPAC
- 2-Chloro-5-fluoronicotinic acid
- Synonyms
- 2-Chloro-5-fluoronicotinic acid
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated pyridine structure for drug discovery and development. Its specific substitution pattern allows for targeted molecular modifications.
Agrochemical Synthesis
Serves as a crucial building block for creating novel pesticides, herbicides, and fungicides. The presence of fluorine can enhance the efficacy and metabolic stability of agrochemical compounds.
Materials Science
Incorporated into the development of functional materials where its unique chemical properties can impart desirable characteristics. Research into new polymers and electronic materials may utilise this compound.
Organic Synthesis Reagent
A versatile reagent for academic and industrial research laboratories undertaking complex organic transformations. It enables the construction of diverse heterocyclic frameworks.
| Molecular weight | 175.54 |
|---|---|
| Empirical formula | C6H3ClFNO2 |
| Grade | technical grade |
| Melting point | 143-144 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 7/9-24/25-26-36/37-38-51 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-fluoropyridine-3-carboxylic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is also employed in materials science and general chemical synthesis research.
What is the CAS number and molecular formula for 2-Chloro-5-fluoropyridine-3-carboxylic acid?
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The CAS number is 38186-88-8 and the molecular formula is C6H3ClFNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a technical grade material. We do not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This chemical is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Wear appropriate personal protective equipment, including gloves, eye protection, and respiratory protection if ventilation is inadequate. Avoid breathing dust.
Is 2-Chloro-5-fluoropyridine-3-carboxylic acid a controlled substance?
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The provided data does not indicate that this substance is a controlled substance.
How can I request a sample or quote for 2-Chloro-5-fluoropyridine-3-carboxylic acid?
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Please contact our sales team via the website or direct email to request a sample or a quotation. Provide your specific requirements for prompt service.
How is this chemical packed and shipped?
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It is packed according to standard industry practices for fine chemicals to ensure safe transport. TSS exports globally, adhering to all relevant shipping regulations.
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