Methylmalonic acid
Methylmalonic acid (CAS 516-05-2), with the chemical formula CH3CH(CO2H)2 and a molecular weight of 118.09 g/mol, is a dicarboxylic acid. It serves as a valuable building block in organic synthesis. This compound is commonly employed in the preparation of various organic molecules and intermediates, contributing to research and development across multiple chemical disciplines.
- IUPAC
- 2-Methylpropanedioic acid
- Synonyms
- 2-Methylpropanedioic acid

Organic Synthesis Intermediate
Methylmalonic acid is utilised as a key intermediate in the synthesis of more complex organic molecules. Its dicarboxylic acid functionality allows for diverse chemical transformations.
Research and Development
This compound is frequently used in laboratory settings for R&D purposes, aiding in the exploration of new chemical pathways and the development of novel compounds.
Building Block for Fine Chemicals
As a C4 building block, methylmalonic acid is integral in the construction of fine chemicals and specialty reagents, supporting innovation in chemical manufacturing.
| Molecular weight | 118.09 |
|---|---|
| Linear formula | CH3CH(CO2H)2 |
| Assay | 99% |
| Melting point | 128-130 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methylmalonic acid used for?
+
Methylmalonic acid is used as a building block and intermediate in organic synthesis and research and development.
What is the CAS number and formula for Methylmalonic acid?
+
The CAS number for Methylmalonic acid is 516-05-2, and its chemical formula is CH3CH(CO2H)2.
What grade and purity does Tech Serve Solutions supply for Methylmalonic acid?
+
Tech Serve Solutions supplies Methylmalonic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards when handling Methylmalonic acid?
+
Methylmalonic acid is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US), should be used.
How is Methylmalonic acid packed and shipped by TSS?
+
Methylmalonic acid is packed and shipped according to industry standards to ensure safe transport and delivery. TSS is a global supplier and exporter.
How can I request a quote or sample of Methylmalonic acid?
+
To request a quote or sample of Methylmalonic acid, please contact our sales team through the website or by phone.
▶ Related products

3,4,5-Trimethoxybenzylamine
Organic Building Blocks

3,4-dihydroxyphenylacetone
Organic Building Blocks

3-Fluoro-4-methoxybenzonitrile
C8H6FNO
Organic Building Blocks
4-Ethyltoluene
C2H5C6H4CH3
Organic Building Blocks
Fluoroacetic acid
C2H3FO2
Organic Building Blocks
Methoxyacetaldehyde
C3H6O2
Organic Building Blocks
Methyl 4-acetamido-5-chloro-2-methoxybenzoate
Organic Building Blocks

Methyl 5-bromo-2-iodobenzoate
BrC6H3(I)CO2CH3
Organic Building Blocks▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis