2-Bromo-2′,4′-dichloroacetophenone
2-Bromo-2′,4′-dichloroacetophenone (CAS: 2631-72-3) is an organic compound with the molecular formula Cl2C6H3COCH2Br and a molecular weight of 267.93 g/mol. This halogenated acetophenone derivative functions primarily as a versatile building block in organic synthesis. It is utilised in the preparation of more complex molecules, particularly within the fields of pharmaceutical research and materials science, owing to its reactive bromoacetyl group and substituted phenyl ring.
- Synonyms
- Cl2C6H3COCH2Br

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of various organic compounds. Its reactive alpha-bromo ketone moiety allows for nucleophilic substitution reactions, enabling the introduction of complex functionalities.
Pharmaceutical Research
Utilised in the development of novel pharmaceutical agents. The compound's structure can be incorporated into potential drug candidates, facilitating research into new therapeutic compounds.
Material Science
Applicable in the synthesis of specialised materials. The functional groups present can be leveraged to create polymers or other advanced materials with tailored properties.
| Molecular weight | 267.93 |
|---|---|
| Linear formula | Cl2C6H3COCH2Br |
| Assay | 97% |
| Melting point | 25-29 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′,4′-dichloroacetophenone used for?
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2-Bromo-2′,4′-dichloroacetophenone is primarily used as a versatile building block in organic synthesis for the preparation of more complex molecules, particularly in pharmaceutical research and materials science.
What are the CAS number and molecular formula for 2-Bromo-2′,4′-dichloroacetophenone?
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The CAS number is 2631-72-3 and the linear molecular formula is Cl2C6H3COCH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-2′,4′-dichloroacetophenone at an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 2-Bromo-2′,4′-dichloroacetophenone be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, face shields, and gloves. This compound is classified as Danger, with hazards including acute toxicity (oral), skin irritation, serious eye damage, and respiratory irritation (H301-H315-H318-H335).
Is 2-Bromo-2′,4′-dichloroacetophenone a controlled substance?
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The provided data does not indicate that 2-Bromo-2′,4′-dichloroacetophenone is a controlled substance.
How is this chemical exported or shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and compliance for international shipments. Specific shipping details are available upon request.
How can I request a quote or sample?
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To request a quote or sample of 2-Bromo-2′,4′-dichloroacetophenone, please contact the Tech Serve Solutions sales team through our website or by phone.
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