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2-Bromo-2-nitro-1,3-propanediol

CAS 52-51-7HOCH2C(Br)(NO2)CH2OHChemical Synthesis

2-Bromo-2-nitro-1,3-propanediol (CAS 52-51-7) is a chemical compound with the linear formula HOCH₂C(Br)(NO₂)CH₂OH and a molecular weight of 199.99 g/mol. This polyol is recognised for its utility as an organic building block in chemical synthesis. Its primary applications involve its use in the development of rapid bacterial toxicity tests and in analytical methods for bromine-containing preservatives.

IUPAC
BNPD,BNPK,Bronopol
Synonyms
Bronopol2-Bromo-2-nitropropane-1,3-diolBNPDBNPK
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2-Bromo-2-nitro-1,3-propanediol (HOCH2C(Br)(NO2)CH2OH) — chemical structure, CAS 52-51-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksOxygen CompoundsPolyols
01 /Applications

Bacterial Toxicity Testing

2-Bromo-2-nitro-1,3-propanediol has been employed in the development of rapid bacterial toxicity tests. These tests are designed to detect disinfectant residues present on disinfected materials, providing a quick assessment of contamination levels.

Analytical Chemistry Reagent

This compound serves as a reagent in advanced analytical techniques. It has been utilised in the rapid analysis of bromine-containing preservatives through methods such as ultra-performance liquid chromatography coupled with inductively coupled plasma mass spectrometry.

Organic Synthesis Intermediate

As an organic building block, 2-Bromo-2-nitro-1,3-propanediol is a valuable intermediate in various chemical synthesis pathways. Its structure lends itself to the creation of more complex organic molecules.

02 /Properties
Molecular weight199.99
Linear formulaHOCH2C(Br)(NO2)CH2OH
Assay98%
SolubilityH2O: soluble100 mg/mL, clear, colorless to faintly yellow
Application2-Bromo-2-nitro-1,3-propanediol was used to develop a rapid bacterial toxicity test for detecting disinfectant residues released by disinfected materials1. It was used in rapid analysis of bromine-containing preservatives by ultra performance liquid chromatography coupled with inductively coupled plasma mass spectrometry2.
Melting point130-133 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation
  • H400Very toxic to aquatic life

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P273Avoid release to the environment
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)UN 3241 4.1 / PGIII
Water hazard class (WGK, DE)2
Hazard codes (EU)Xn,N
Risk statements (R)21/22-37/38-41-50
Safety statements (S)26-36/37/39-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
52-51-7
MDL number
MFCD00007390
PubChem substance
24848173
Beilstein registry
1705868
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What are the primary applications of 2-Bromo-2-nitro-1,3-propanediol?

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2-Bromo-2-nitro-1,3-propanediol is primarily used in the development of rapid bacterial toxicity tests for detecting disinfectant residues and in analytical chemistry for the analysis of bromine-containing preservatives. It also serves as an organic building block in chemical synthesis.

What is the CAS number and chemical formula for 2-Bromo-2-nitro-1,3-propanediol?

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The CAS number is 52-51-7 and the linear formula is HOCH₂C(Br)(NO₂)CH₂OH.

What grade and purity does Tech Serve Solutions supply for 2-Bromo-2-nitro-1,3-propanediol?

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Tech Serve Solutions supplies 2-Bromo-2-nitro-1,3-propanediol with an assay of 98%. This is a technical/research grade material, and we do not represent it as USP, BP, EP, or pharmacopoeia grade.

What are the main safety hazards associated with 2-Bromo-2-nitro-1,3-propanediol?

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2-Bromo-2-nitro-1,3-propanediol is classified with the following hazards: harmful if swallowed (H302), harmful in contact with skin (H312), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). It is also very toxic to aquatic life (H400). Appropriate personal protective equipment including a dust mask (type N95), eyeshields, face shields, and gloves should be used when handling this compound.

Can Tech Serve Solutions export 2-Bromo-2-nitro-1,3-propanediol?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, and can facilitate export of 2-Bromo-2-nitro-1,3-propanediol.

How can I request a quote or sample of 2-Bromo-2-nitro-1,3-propanediol?

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Please contact our sales department via the website or telephone to request a quote or a sample of 2-Bromo-2-nitro-1,3-propanediol.

Need 2-Bromo-2-nitro-1,3-propanediol in a specific grade or volume?