3-Methoxyphenylmagnesium bromide solution
3-Methoxyphenylmagnesium bromide solution (CAS 36282-40-3, CH₃OC₆H₄MgBr) is an organometallic reagent supplied by Tech Serve Solutions (TSS) at a concentration of 1.0 M in THF. This Grignard reagent is a valuable tool in organic synthesis, primarily employed for the introduction of the 3-methoxyphenyl group into various organic molecules. Its utility spans the synthesis of complex organic compounds and pharmaceutical intermediates. The compound is flammable and corrosive, requiring careful handling.
Grignard Reagent in Organic Synthesis
3-Methoxyphenylmagnesium bromide solution serves as a potent nucleophile for forming new carbon-carbon bonds. It is widely used to introduce the 3-methoxyphenyl moiety into carbonyl compounds, epoxides, and other electrophilic substrates.
Pharmaceutical Intermediate Synthesis
This reagent is instrumental in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules. Its application aids in building the core structures of various therapeutic agents.
Synthesis of Fine Chemicals
In the production of fine chemicals, 3-Methoxyphenylmagnesium bromide solution facilitates the creation of specialized organic compounds with tailored properties for diverse industrial applications.
| Molecular weight | 211.34 |
|---|---|
| Linear formula | CH3OC6H4MgBr |
| Boiling point | 65-67 °C |
| Density | 1.013 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methoxyphenylmagnesium bromide solution used for?
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3-Methoxyphenylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis for introducing the 3-methoxyphenyl group into various organic molecules, and in the synthesis of pharmaceutical intermediates and fine chemicals.
What are the CAS number and chemical formula for 3-Methoxyphenylmagnesium bromide solution?
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The CAS number is 36282-40-3, and the linear chemical formula is CH₃OC₆H₄MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methoxyphenylmagnesium bromide solution at a concentration of 1.0 M in THF. We do not represent this product as USP, BP, or EP grade.
How should 3-Methoxyphenylmagnesium bromide solution be handled safely?
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This compound is flammable and corrosive. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, and a face shield. Avoid contact with water as it reacts violently.
How is this chemical packed, shipped, and exported?
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As a specialist global supplier, TSS ensures secure packaging for safe transport and export, adhering to all relevant regulations for hazardous materials. Please contact us for specific details.
How can I request a sample or quote for 3-Methoxyphenylmagnesium bromide solution?
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To request a sample or quote, please contact our sales team through the TSS website or by phone, providing your specific requirements.
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