2-Bromo-2′,4′-difluoroacetophenone
2-Bromo-2′,4′-difluoroacetophenone (CAS: 102429-07-2) is a fluorinated aromatic ketone with the molecular formula C<sub>6</sub>H<sub>3</sub>(F<sub>2</sub>)COCH<sub>2</sub>Br and a molecular weight of 235.03 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly within the fields of medicinal chemistry and materials science. Its reactive bromoacetyl group makes it a key building block for introducing difluorophenyl motifs into more complex molecular structures.
- Synonyms
- C6H3(F2)COCH2Br
Pharmaceutical Intermediate
Used in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs). Its difluorophenyl moiety can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Synthesis
Can serve as a building block for the development of new pesticides, herbicides, and fungicides, where fluorinated groups often enhance biological activity.
Materials Science Research
Employed in the creation of advanced materials, potentially including polymers or specialty organic compounds with unique electronic or optical properties due to the presence of fluorine atoms.
Organic Synthesis Reagent
A versatile reagent for introducing the 2,4-difluorobenzoylmethyl group into various organic molecules through nucleophilic substitution reactions.
| Molecular weight | 235.03 |
|---|---|
| Linear formula | C6H3(F2)COCH2Br |
| Assay | 97% |
| Melting point | 31-35 °C(lit.) |
Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 2925 4.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′,4′-difluoroacetophenone used for?
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2-Bromo-2′,4′-difluoroacetophenone is primarily used as an intermediate and building block in organic synthesis, notably in the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and chemical formula for this product?
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The CAS number is 102429-07-2, and the chemical formula is C<sub>6</sub>H<sub>3</sub>(F<sub>2</sub>)COCH<sub>2</sub>Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-2′,4′-difluoroacetophenone with a minimum assay of 97%. This is suitable for research and synthesis purposes; TSS does not represent this product as USP, BP, or EP grade.
How should 2-Bromo-2′,4′-difluoroacetophenone be handled safely?
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This compound is a Danger hazard (H228, H302, H314). It is flammable, harmful if swallowed, and causes severe skin burns and eye damage. Always use appropriate personal protective equipment including eyeshields, face shields, chemical-resistant gloves, and a suitable respirator. Ensure adequate ventilation and avoid ignition sources.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Bromo-2′,4′-difluoroacetophenone. We ship to numerous international destinations.
How can I request a quotation or sample?
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To request a quotation or a sample of 2-Bromo-2′,4′-difluoroacetophenone, please visit our website or contact our sales department directly with your inquiry.
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