2-Bromo-2′,5′-dimethoxyacetophenone
2-Bromo-2′,5′-dimethoxyacetophenone (CAS: 1204-21-3) is a useful organic intermediate. With the molecular formula (CH₃O)₂C₆H₃COCH₂Br and a molecular weight of 259.10 g/mol, this compound serves as a valuable building block in chemical synthesis. It is typically employed in the development of more complex molecules within research and industrial settings, offering a reactive site for further chemical transformations.
- Synonyms
- (CH3O)2C6H3COCH2Br

Organic Synthesis Intermediate
2-Bromo-2′,5′-dimethoxyacetophenone is a versatile building block in organic synthesis. Its reactive bromoacetyl group allows for various coupling and derivatization reactions, facilitating the construction of complex molecular structures.
Pharmaceutical Research
This compound can be utilised in the early stages of pharmaceutical research and development. It serves as a starting material or intermediate for the synthesis of potential drug candidates and biologically active molecules.
Materials Science
As a functionalized aromatic ketone, 2-Bromo-2′,5′-dimethoxyacetophenone may find applications in materials science, contributing to the synthesis of novel polymers or functional materials with specific properties.
| Molecular weight | 259.10 |
|---|---|
| Linear formula | (CH3O)2C6H3COCH2Br |
| Assay | 97% |
| Melting point | 83-85 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-27-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′,5′-dimethoxyacetophenone used for?
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2-Bromo-2′,5′-dimethoxyacetophenone is primarily used as an intermediate and building block in organic synthesis, including pharmaceutical research and potentially in materials science.
What is the CAS number and molecular formula for 2-Bromo-2′,5′-dimethoxyacetophenone?
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The CAS number is 1204-21-3 and the molecular formula is (CH₃O)₂C₆H₃COCH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-2′,5′-dimethoxyacetophenone with an assay of 97%. This is a research grade material and is not represented as USP, BP, or EP.
How should 2-Bromo-2′,5′-dimethoxyacetophenone be handled?
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Handle with care. It is classified as an irritant to skin, eyes, and respiratory system (H315-H319-H335) and is harmful to aquatic life (H400). Use appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid release to the environment.
How is 2-Bromo-2′,5′-dimethoxyacetophenone packed and exported?
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As a global supplier, Tech Serve Solutions professionally packs and exports chemicals worldwide, adhering to international shipping regulations for hazardous materials (UN 3077 9/PGIII).
How can I request a sample or quote for 2-Bromo-2′,5′-dimethoxyacetophenone?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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