2-Bromo-2′-fluoroacetophenone
2-Bromo-2′-fluoroacetophenone (CAS 655-15-2) is a chemical compound with the molecular formula C8H6BrFO and a molecular weight of 217.04 g/mol. This fluorinated aryl ketone serves as a valuable building block in organic synthesis, particularly for the introduction of the 2-fluorophenacyl moiety into more complex molecules. Its reactivity profile makes it suitable for various chemical transformations in research and development settings.
- IUPAC
- α-Bromo-2-fluoroacetophenone,ω-Bromo-2-fluoroacetophenone,1-Bromo-2′;-fluoroacetophenone,2-Bromo-1-(2-fluorophenyl)ethanone,2-Fluorophenacyl bromide,o-Fluorophenacyl bromide
- Synonyms
- α-Bromo-2-fluoroacetophenoneω-Bromo-2-fluoroacetophenone1-Bromo-2′-fluoroacetophenone2-Bromo-1-(2-fluorophenyl)ethanone2-Fluorophenacyl bromideo-Fluorophenacyl bromide
Organic Synthesis Intermediate
This compound is utilised as a key intermediate in the synthesis of diverse organic molecules. Its structure allows for further functionalization, making it adaptable for creating novel compounds in pharmaceutical and agrochemical research.
Fluorinated Building Block
As a fluorinated building block, 2-Bromo-2′-fluoroacetophenone enables the incorporation of fluorine atoms into target molecules. This is often desirable in medicinal chemistry to modulate pharmacokinetic properties and biological activity.
Research and Development
It finds application in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities. Its specific reactivity profile supports a range of chemical reactions.
| Molecular weight | 217.04 |
|---|---|
| Empirical formula | C8H6BrFO |
| Assay | 97% |
| Density | 1.574 g/mL at 25 °C |
| Refractive index | n20/D 1.563 |
| Storage temperature | 2-8°C |
| Melting point | 25-30 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′-fluoroacetophenone used for?
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2-Bromo-2′-fluoroacetophenone is primarily used as a chemical intermediate and building block in organic synthesis, particularly in research and development for creating fluorinated organic molecules.
What is the CAS number and molecular formula for 2-Bromo-2′-fluoroacetophenone?
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The CAS number is 655-15-2 and the molecular formula is C8H6BrFO.
What grade and purity does Tech Serve Solutions supply for 2-Bromo-2′-fluoroacetophenone?
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Tech Serve Solutions supplies 2-Bromo-2′-fluoroacetophenone with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the main hazards associated with 2-Bromo-2′-fluoroacetophenone?
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2-Bromo-2′-fluoroacetophenone is classified as Danger, with hazard statement H314, indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment (PPE) must be worn during handling.
How is 2-Bromo-2′-fluoroacetophenone packed and exported?
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This chemical is packed and exported in compliance with relevant transport regulations, such as UN 3261, Class 8, Packing Group III. Storage is recommended at 2-8°C.
How can I request a quote or sample for 2-Bromo-2′-fluoroacetophenone?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your requirements and shipping details.
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