2-Bromo-2′-methoxyacetophenone
2-Bromo-2′-methoxyacetophenone (CAS 31949-21-0) is a brominated ketone with the molecular formula C<sub>9</sub>H<sub>9</sub>BrO<sub>2</sub> and a molecular weight of 229.07 g/mol. This compound serves as a valuable building block in organic synthesis. Its reactive bromoacetyl group and methoxy-substituted phenyl ring allow for diverse chemical transformations, making it useful in the preparation of more complex molecules within chemical research and development.
- IUPAC
- 2′-Methoxyphenacyl bromide
- Synonyms
- 2′-Methoxyphenacyl bromide1-(2-Methoxyphenyl)-2-bromoethanone

Organic Synthesis Intermediate
2-Bromo-2′-methoxyacetophenone is employed as a key intermediate in the synthesis of various organic compounds. Its structure facilitates reactions like alkylation and acylation, enabling the construction of novel molecular architectures.
Pharmaceutical Research
This compound finds application in the early stages of drug discovery and development. It can be used to synthesize potential drug candidates or intermediates for active pharmaceutical ingredients (APIs) where its specific structural features are required.
Material Science
The unique functional groups present in 2-Bromo-2′-methoxyacetophenone may be utilised in the development of specialised materials. Its reactivity can be exploited to introduce specific properties into polymers or other advanced materials.
| Molecular weight | 229.07 |
|---|---|
| Linear formula | CH3OC6H4COCH2Br |
| Assay | 98% |
| Boiling point | 130 °C/1 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 43-45 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′-methoxyacetophenone used for?
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2-Bromo-2′-methoxyacetophenone is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and the development of novel organic compounds.
What are the CAS number and molecular formula for 2-Bromo-2′-methoxyacetophenone?
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The CAS number for 2-Bromo-2′-methoxyacetophenone is 31949-21-0, and its linear molecular formula is C<sub>9</sub>H<sub>9</sub>BrO<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-2′-methoxyacetophenone with a minimum assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product documentation.
How should 2-Bromo-2′-methoxyacetophenone be handled safely?
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2-Bromo-2′-methoxyacetophenone is classified as corrosive (H314). Handle with extreme care, using appropriate personal protective equipment including safety goggles, face shields, and chemically resistant gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports 2-Bromo-2′-methoxyacetophenone according to international regulations for hazardous materials. It is classified under UN 3261, Class 8, Packing Group II. We ensure compliant packaging and documentation for global distribution.
How can I request a sample or a quote for 2-Bromo-2′-methoxyacetophenone?
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To request a sample or a quote for 2-Bromo-2′-methoxyacetophenone, please contact our sales team via the website or direct email, providing your contact details and the quantity required.
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