2-Bromo-2′-nitroacetophenone
2-Bromo-2′-nitroacetophenone (CAS: 6851-99-6) is a chemical compound with the molecular formula O₂NC₆H₄COCH₂Br and a molecular weight of 244.04 g/mol. This ketone derivative serves as a valuable building block in organic synthesis. It is particularly noted for its utility as an electroactive derivative-forming reagent, enabling the preparation of complex molecules, including prostaglandins.
- IUPAC
- 2′-Nitrophenacyl bromide
- Synonyms
- 2′-Nitrophenacyl bromide
Derivative Formation
2-Bromo-2′-nitroacetophenone is employed as a precolumn derivatization reagent. This application is crucial in analytical chemistry for enhancing the detectability of certain analytes.
Prostaglandin Synthesis
This compound has been utilised in the preparation of prostaglandin derivatives. Its reactive nature allows for the introduction of specific functionalities necessary for prostaglandin synthesis.
Organic Synthesis Building Block
As a ketone with both bromo and nitro functionalities, 2-Bromo-2′-nitroacetophenone acts as a versatile building block. It facilitates the construction of more complex organic structures through various synthetic transformations.
| Molecular weight | 244.04 |
|---|---|
| Linear formula | O2NC6H4COCH2Br |
| Assay | 99% |
| Application | 2-Bromo-2′-nitroacetophenone, an electroactive derivative-forming reagent, was used as a precolumn reagent for preparing prostaglandin derivatives1. |
| Melting point | 55-57 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-2′-nitroacetophenone used for?
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2-Bromo-2′-nitroacetophenone is used as a building block in organic synthesis and as an electroactive derivative-forming reagent, notably in the preparation of prostaglandin derivatives.
What is the CAS number and chemical formula for 2-Bromo-2′-nitroacetophenone?
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The CAS number is 6851-99-6, and its linear formula is O₂NC₆H₄COCH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-2′-nitroacetophenone with a purity of 99% (assay). We do not represent this product as USP, BP, or EP grade.
How should 2-Bromo-2′-nitroacetophenone be handled?
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This compound is classified as corrosive and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, must be used. Handle in a well-ventilated area.
How is 2-Bromo-2′-nitroacetophenone shipped and exported?
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2-Bromo-2′-nitroacetophenone is shipped according to UN 3261, Class 8, Packing Group II regulations, indicating it is a corrosive solid, acidic, organic, n.o.s. Tech Serve Solutions exports globally.
How can I request a quote or sample for 2-Bromo-2′-nitroacetophenone?
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Please contact our sales team via the website or direct email to request a quote or sample for 2-Bromo-2′-nitroacetophenone.
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