2,5-Bis(trifluoromethyl)benzoyl chloride
2,5-Bis(trifluoromethyl)benzoyl chloride (CAS: 393-82-8) is a fluorinated organic compound with the molecular formula (CF3)2C6H3COCl and a molecular weight of 276.56 g/mol. This reactive acid halide serves as a valuable building block in organic synthesis. Its trifluoromethyl groups impart unique electronic and lipophilic properties, making it useful in the preparation of complex molecules, particularly in agrochemical and pharmaceutical research.
- Synonyms
- (CF3)2C6H3COCl

Organic Synthesis Intermediate
Utilized as a key intermediate for introducing the 2,5-bis(trifluoromethyl)benzoyl moiety into various organic structures. Its reactivity allows for facile acylation reactions.
Agrochemical Research
Serves as a precursor in the synthesis of novel pesticide and herbicide candidates, leveraging the influence of trifluoromethyl groups on biological activity.
Pharmaceutical Development
Employed in the development of new drug candidates where the unique electronic and lipophilic properties conferred by the bis(trifluoromethyl)phenyl group are desired.
Material Science
Can be used in the synthesis of specialty polymers or functional materials requiring high thermal stability or specific electronic characteristics.
| Molecular weight | 276.56 |
|---|---|
| Linear formula | (CF3)2C6H3COCl |
| Assay | 97% |
| Density | 1.528 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4315(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Bis(trifluoromethyl)benzoyl chloride used for?
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2,5-Bis(trifluoromethyl)benzoyl chloride is primarily used as a reactive intermediate and building block in organic synthesis, particularly in the research and development of agrochemicals and pharmaceuticals.
What is the CAS number and formula for 2,5-Bis(trifluoromethyl)benzoyl chloride?
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The CAS number is 393-82-8, and its linear formula is (CF3)2C6H3COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Bis(trifluoromethyl)benzoyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2,5-Bis(trifluoromethyl)benzoyl chloride be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, goggles, a faceshield, and a suitable respirator. Ensure good ventilation and avoid contact with moisture.
Is 2,5-Bis(trifluoromethyl)benzoyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,5-Bis(trifluoromethyl)benzoyl chloride, adhering to all relevant shipping regulations, such as UN 3265, Class 8, Packing Group II.
How can I request a quote or sample?
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To request a quote or sample of 2,5-Bis(trifluoromethyl)benzoyl chloride, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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