Glycolide
Glycolide (CAS: 502-97-6, C4H4O4) is a cyclic diester with a molecular weight of 116.07 g/mol. It serves as a crucial monomer in the synthesis of biodegradable polymers, most notably polylactic-co-glycolic acid (PLGA). Its controlled ring-opening polymerization yields materials with tunable degradation rates, making it valuable in biomedical applications and advanced materials science. TSS supplies Glycolide at a purity of ≥99%.
- IUPAC
- 1,4-Dioxane-2,5-dione
- Synonyms
- 1,4-Dioxane-2,5-dione
Biodegradable Polymer Synthesis
Glycolide is a primary monomer for producing polyglycolic acid (PGA) and copolymers like PLGA. These polymers are valued for their biocompatibility and biodegradability, finding extensive use in medical devices and drug delivery systems.
Biomedical Applications
The polymers derived from glycolide are employed in sutures, tissue engineering scaffolds, and controlled-release formulations. Their degradation into non-toxic by-products is key to these applications.
Materials Science
As a monomer, glycolide contributes to the development of novel biodegradable and functional materials. Research focuses on tailoring polymer properties for specific advanced material requirements.
| Molecular weight | 116.07 |
|---|---|
| Empirical formula | C4H4O4 |
| Assay | ≥99% |
| Storage temperature | −20°C |
| Melting point | 82-86 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycolide used for?
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Glycolide is primarily used as a monomer in the synthesis of biodegradable polymers such as polyglycolic acid (PGA) and poly(lactic-co-glycolic acid) (PLGA), which have significant applications in biomedical devices and materials science.
What is the CAS number and formula for Glycolide?
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The CAS number for Glycolide is 502-97-6 and its empirical formula is C4H4O4.
What grade and purity does Tech Serve Solutions supply for Glycolide?
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Tech Serve Solutions supplies Glycolide with an assay of ≥99%. We do not represent this product as meeting any specific pharmacopoeia standards (USP, EP, BP) unless explicitly stated in the product documentation.
What are the safety and handling considerations for Glycolide?
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Glycolide is classified as harmful if swallowed and causes serious eye irritation (H302, H319). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area and avoid dust formation. In case of contact, follow precautionary statements P305 + P351 + P338.
How is Glycolide shipped and exported by TSS?
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Glycolide is shipped in dry ice to maintain its stability during transit and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample of Glycolide?
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To request a quote or a sample of Glycolide, please contact the Tech Serve Solutions sales team through our website or by phone.
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