Hexaethylene glycol di-p-toluenesulfonate
Hexaethylene glycol di-p-toluenesulfonate (CAS: 42749-27-9) is a homobifunctional poly(ethylene glycol) derivative with the molecular formula C26H38O11S2. Its structure features two tosylate end groups, making it a versatile building block in polymer chemistry and materials science. This compound is primarily employed in cross-linking applications, surface modification, and as a linker in the synthesis of complex molecules and polymers.
- IUPAC
- HEG ditosylate,Hexaethylene glycol ditosylate
- Synonyms
- HEG ditosylate, Hexaethylene glycol ditosylate

Polymer Synthesis
Hexaethylene glycol di-p-toluenesulfonate serves as a monomer or cross-linking agent in the synthesis of specialized polymers, particularly those based on poly(ethylene glycol) architectures. The tosylate groups provide reactive sites for nucleophilic substitution reactions.
Surface Modification
This ditosylate can be used to functionalise surfaces, introducing poly(ethylene glycol) chains. This is valuable for applications requiring altered surface properties such as hydrophilicity or biocompatibility.
Linker in Organic Synthesis
As a homobifunctional reagent, it acts as a flexible linker molecule for connecting two different molecular entities in multi-step organic syntheses, including the preparation of complex pharmaceutical intermediates.
Materials Science Research
Its utility extends to materials science for developing novel materials with tailored properties, leveraging the characteristics of the PEG backbone and the reactive tosylate end-groups.
| Molecular weight | 590.70 |
|---|---|
| Empirical formula | C26H38O11S2 |
| Assay | >97% |
| Density | 1.227 g/mL at 25 °C |
| Refractive index | n20/D 1.521 |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexaethylene glycol di-p-toluenesulfonate used for?
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Hexaethylene glycol di-p-toluenesulfonate is used in polymer synthesis, surface modification, as a linker in organic synthesis, and in materials science research.
What are the CAS number and chemical formula for Hexaethylene glycol di-p-toluenesulfonate?
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The CAS number is 42749-27-9 and the chemical formula is C26H38O11S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hexaethylene glycol di-p-toluenesulfonate with an assay of >97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Hexaethylene glycol di-p-toluenesulfonate be handled safely?
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This compound has a flash point above 110 °C (230 °F) and is classified with WGK Germany 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling and safety information.
Is this chemical a controlled substance?
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The provided data does not indicate that Hexaethylene glycol di-p-toluenesulfonate is a controlled substance.
How is Hexaethylene glycol di-p-toluenesulfonate packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations and exported worldwide.
How can I request a quote or sample for this product?
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To request a quote or sample of Hexaethylene glycol di-p-toluenesulfonate, please contact our sales department via the website or by telephone.
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